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Skip to Search Results- 2Errington, Wesley J.
- 2Macauley, Matthew S.
- 2Mackereth, Cameron D.
- 2Schärpf, Manuela
- 1Blaszczak, Adam G.
- 1Graves, Barbara J.
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Beads-on-a-string, characterization of ETS-1 sumoylated within its flexible N-terminal sequence
Download2006
Mackereth, Cameron D., Graves, Barbara J., Macauley, Matthew S., Schärpf, Manuela, McIntosh, Lawrence P. , Blaszczak, Adam G., Errington, Wesley J.
Sumoylation regulates the activities of several members of the ETS transcription factor family. To provide a molecular framework for understanding this regulation, we have characterized the conjugation of Ets-1 with SUMO-1. Ets-1 is modified in vivo predominantly at a consensus sumoylation motif...
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2004
Okon, Mark, Schulman, Brenda A., Macauley, Matthew S., McIntosh, Lawrence P., Mackereth, Cameron D., Schärpf, Manuela, Errington, Wesley J.
Although sumoylation regulates a diverse and growing number of recognized biological processes, the molecular mechanisms by which the covalent attachment of the ubiquitin-like protein SUMO can alter the properties of a target protein remain to be established. To address this question, we have...