Journal Articles (Chemistry)

2014

Macauley, M. S., Cheng, T. Y., Moody, D. B., Paulson, J. C. , Kawasaki, N., Van Rhijn, I., Rillahan, C. D.

Lipids from mycobacteria can be presented to human T cells by group 1 CD1 Ag-presenting molecules (CD1a, CD1b, and CD1c). Group 1 CD1-restricted T cells are activated by lipid Ags presented by myeloid dendritic cells (DCs), after which they generate antibacterial effector functions, including...

2016

O’Dwyer, Michael E., Macauley, Matthew S., Natoni, Alessandro

Aberrant glycosylation is a hallmark of cancer cells with increased evidence pointing to a role in tumor progression. In particular, aberrant sialylation of glycoproteins and glycolipids has been linked to increased immune cell evasion, drug evasion, drug resistance, tumor invasiveness, and...

2013-01-01

El-Yazbi, Amira F., Loppnow, Glen R.

Much effort has been focused on developing methods for detecting damaged nucleic acids. However, almost all of the proposed methods consist of multi-step procedures, are limited, require expensive instruments, or suffer from a high level of interferences. In this paper, we present a novel simple,...

2022-01-01

Bozheng Sun, Meagan S. Oakley, Kota Yoshida, Yanwen Yang, Matteo Tommasini, Chiara Zanchi, Andrea Lucotti, Michael J. Ferguson, Frank Hampel, Mariusz Klobukowski, and Rik R. Tykwinski

Cyclic tetraaryl[5]cumulenes (1a–f) have been synthesized and studied as a function of increasing ring strain. The magnitude of ring strain is approximated by the extent of bending of the cumulenic core as assessed by a combination of X-ray crystallographic analysis and DFT calculations. Trends...

2013-01-01

Hu, Liang, Serpe, Michael J.

Poly(N-isopropylacrylamide)-co-acrylic acid (pNIPAm-co-AAc) microgel-based thin films and etalons were fabricated via “painting” a pNIPAm-co-AAc microgel monolayer on a Au-coated substrate, followed by the deposition of another Au overlayer. Herein, in situ observation of how the pH and ionic...

2016-01-01

Xiao Qin Lee, P. Mark L. Sandercock, James J. Harynuk

We have previously demonstrated the successful application of multivariate statistical(i.e. chemometric) techniques to the classification of casework fire debris based on gasoline content, with the objective to expedite the data interpretation process for the forensic analysis of fire debris. We...

2013

Deng, Lu, Klassen, John S., Kitova, Elena N., Sinelnikov, Igor

The results of time-resolved blackbody infrared radiative dissociation experiments performed on gaseous protonated ions, at charge states +15, +16 and +17, of the homotetramer streptavidin (S4) are reported. Evidence is found for three dissociation pathways involving (i) the loss of a single...

2013

Klassen, John S., Sinelnikov, Igor, Kitova, Elena N., Deng, Lu

The results of time-resolved blackbody infrared radiative dissociation experiments performed on gaseous protonated ions, at charge states +15, +16 and +17, of the homotetramer streptavidin (S4) are reported. Evidence is found for three dissociation pathways involving (i) the loss of a single...

2015

Xiao, Changchun., Gonzalez-Martin, Alicia, Miletic, Ana V., Rickert, Robert C., Head, Steven R., Knight, Sarah, , Macauley, Matthew S., Lai, Maoyi, Jin, Hyun Y., Sabouri-Ghomi, Mohsen

Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used extensively to study the functions and mechanisms of endogenous miRNAs. However, it remains unclear whether transfected miRNAs behave similarly to endogenous miRNAs. Here we show that transient transfection of...

2015

Zhong, Weiming, Quigley, Christina, Klassen, John S., Fang, Hao, Jiang, Xi, Wei, Chao, Tan, Ming, Xia, Ming, Huang, Pengwei, Fan, Qiang, Zhang, Xufu

The recent discovery that human noroviruses (huNoVs) recognize sialic acids (SAs) in addition to histo-blood group antigens (HBGAs) pointed to a new direction in studying virus-host interactions during calicivirus infection. HuNoVs remain difficult to study due to the lack of an effective cell...