General Internal Medicine
Items in this Collection
- 2Cardiac Troponin
- 2Chemical cleavage
- 2Fusion protein expression
- 2Intrinsically disordered regions
- 2Myocardial Infarction
- 2Randomized Controlled Trials as Topic
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Cost-Utility of Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure: An Economic Evaluation - TreeAge Model
Cost-Utility of Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure: An Economic Evaluation - TreeAge Model
Download2020-01-01
Economic evaluation model to accompany paper entitled Cost-Utility of Catheter Ablation for Atrial Fibrillation in Patients with Heart Failure: An Economic Evaluation (Lau D, Sandhu RK, Andrade JG, Ezekowitz J, So H, Klarenbach S).
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Incidence of Catheter-Related VTE in Acute Leukemia Patients Requiring Peripherally-Inserted Central Catheter
Download2015-05-21
Resident research day for Core Internal Medicine. Background- Central venous catheters (CVCs) are a leading cause of upper extremity deep vein thrombosis (UE DVT). Long term CVCs are required for chemotherapy in acute leukemia (AL), who can be thrombocytopenic which makes anticoagulation for CVC...
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2019-06-01
Guo, Selynne, Hansen, Heather, Khera, Sheny, Rolfson, Darryl
Introduction: As one of the geriatric giants, frailty is a state of decreased physiological reserve and increased vulnerability that results from the collective decline in multiple systems. It manifests as a heterogeneous, multidimensional syndrome. However, several studies have shown that older...
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2018-02-13
Somaya Zahran, Richard Schulz, Michelle M. Graham, Peter M. Hwang, Vivian P. Figueiredo
Background: The serum troponin assay is the biochemical gold standard for detecting myocardial infarction (MI). A major diagnostic issue is that some believe troponin levels can rise with reversible injury, in the absence of radiologically detectable infarct. Hypothesis: Because cell death...
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Quality of Life (QOL) in Diabetics with Multi-Vessel Coronary Artery Disease: Real-World Experience Comparing Percutaneous Coronary Intervention (PCI) and Coronary Artery Bypass Grafting (CABG)
Download2015
Introduction Studies demonstrate mortality benefit supporting CABG over PCI in diabetics with multi-vessel CAD. However, CABG is associated with longer recovery and higher stroke rates. Thus, while CABG prolongs life it’s impact on QOL warrants study. This study utilizes comprehensive...
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Recombinant expression of the cardiac troponin I fragment, cTnI[135-209], that controls cardiac contraction
Download2015-05-14
Jonathan S. Pan, Somaya Zahran, Peter M Hwang
Intrinsically disordered regions (IDRs) are protein segments that lack a fixed three-dimensional structure under physiologic conditions, they are susceptible to post-translational modifications such as proteolysis. However, they are highly important in cellular signal transduction and the...
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Troponin degradation products: more specific marker for myocardial infarction
2017-04-01
Somaya Zahran, Vivian Figueiredo, Michelle Graham, Peter M Hwang, George Cembrowski, Richard Schulz
Introduction Myocardial infarction (MI) is the death of cardiac muscle in the setting of severe ischemia (lack of oxygen and nutrient supply). Assay of serum troponin I (TnI) is the biochemical gold standard for detecting MI. With the development of high sensitivity assays, TnI is being detected...