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Skip to Search Results- 28Greiner, Russell (Computing Science)
- 15Szepesvari, Csaba (Computing Science)
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- 1Andras Gyorgy (Imperial College London, U.K.)
- 1Bolduc, Francois (Pediatrics)
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- 10Machine Learning
- 10Machine learning
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- 4Reinforcement Learning
- 3Learning theory
- 2Diagnosis
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Spring 2010
This thesis presents Pathway Informed Analysis (PIA), a classification method for predicting disease states (diagnosis) from metabolic profile measurements that incorporates biological knowledge in the form of metabolic pathways. A metabolic pathway describes a set of chemical reactions that...
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Addressing the Challenges of Applying Machine Learning for Predicting Mental Disorders and Their Prognosis Using Two Case Studies
DownloadSpring 2019
Ghoreishiamiri, Seyedehreyhaneh
One of the principal applications of machine learning in psychiatry is to build automated tools that can help clinicians predict the diagnosis and prognosis of mental disorders using available data from patients’ profiles. Here, in two different studies, we investigate ways to use machine learn-...
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Spring 2019
Forouzandehmoghadam, Amirhosein
A biomarker is a feature (e.g., gene expression, SNP, etc.) that is significantly different between two classes of instances – typically case and control. Knowing these biomarkers can help us understand a biological condition or identify the appropriate treatment for a certain disease. Many...
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Assessing the Feasibility of Learning Biomedical Phenotype Patterns Using High-Throughput Omics Profiles
DownloadSpring 2014
A decade after the completion of the human genome project, the rapid advancement of the high-throughput measurement technologies has made omics (genomics, epigenomics, transcriptomics, metabolomics) profiling feasible. The availability of such omics profiles has raised the hope for the...
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Spring 2017
Optimizing an objective function over convex sets is a key problem in many different machine learning models. One of the various kinds of well studied objective functions is the convex function, where any local minimum must be the global mini- mum over the domain. To find the optimal point that...
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Building an expert-system based conversational agent to provide personalised resources about neurological disorders
DownloadSpring 2022
Researchers developing artificially intelligent conversational agents (aka, chat- bots) seek effective ways to provide personal assistance to users with various needs. We have implemented a web-based conversational agent that recom- mends resources to help clients (caregivers of patients...
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Spring 2016
One of the key obstacles to the effective use of mass spectrometry (MS) in high throughput metabolomics is the difficulty in interpreting measured spectra to accurately and efficiently identify metabolites. Traditional methods for automated metabolite identification compare the target MS spectrum...
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Spring 2017
Most machine learning problems can be posed as solving a mathematical program that describes the structure of the prediction problem, usually expressed in terms of carefully chosen losses and regularizers. However, many machine learning problems yield mathematical programs that are not convex in...
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Fall 2016
This thesis explores theoretical, computational, and practical aspects of convex (shape-constrained) regression, providing new excess risk upper bounds, a comparison of convex regression techniques with theoretical guarantee, a novel heuristic training algorithm for max-affine representations,...
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Fall 2023
A survival dataset describes a collection of instances, such as patients, and associates each instance with either the time until an event (such as death), or the censoring time (eg, when the instance is lost to follow-up), which is a lower bound on the time until the event. While there are...