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Fall 2018
Partial Bladder Outlet Obstruction (pBOO) is characterized by an initial inflammatory response which progresses to smooth muscle hypertrophy, and fibrosis. The resulting high urine storage pressure significantly damages the bladder wall and poses a risk of renal failure. pBOO is characterized by...
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Novel Mediators and Medical Prevention of Bladder Fibrosis After Partial Bladder Outlet Obstruction
DownloadFall 2012
Introduction: Partial bladder outlet obstruction (pBOO) is a significant problem that can affect renal health. We hypothesize that changes occur in small leucine-rich proteoglycan (SLRP) composition of extracellular matrix over time in this process. We hypothesize that medical treatment of...
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The Proteome of Partial Bladder Outlet Obstruction & The Therapeutic Role of Mesenchymal Stem Cells
DownloadFall 2013
Introduction: Partial bladder outlet obstruction (pBOO) is a common problem in urology. It passes through several pathological phases before progressing to bladder fibrosis. Herein, we investigated the proteomic profile of the urinary bladder in the early phase after pBOO, and examined the...