Search
Skip to Search Results- 1Abou Zeinab, Rami M
- 1Abuetabh, Yasser H
- 1Al Yousef, Habib Saleh M
- 1Albahrani, Redha Mohammed
- 1Allen,Richelle J
- 1Almizraq, Ruqayyah J
- 26Medical Sciences-Laboratory Medicine and Pathology
- 25Medical Sciences- Laboratory Medicine and Pathology
- 5Medical Sciences - Laboratory Medicine and Pathology
- 1Chemical and Materials Engineering and Medical Sciences - Laboratory Medicine and Pathology
- 1Medical Science - Laboratory Medicine and Pathology
- 1Medical Sciences – Laboratory Medicine and Pathology
- 5Li, Xing-Fang (Laboratory Medicine and Pathology)
- 4Damaraju, Sambasivarao (Laboratory Medicine and Pathology)
- 4Lai, Raymond (Laboratory Medicine and Pathology)
- 3Acker, Jason (Laboratory Medicine and Pathology)
- 3Le, X. Chris (Laboratory Medicine and Pathology)
- 3Leng, Roger (Laboratory Medicine and Pathology)
Results for "departments_tesim:"Medical Sciences- Laboratory Medicine and Pathology""
-
Characterization of the Paradoxical Growth Effect of Candida albicans Exposed to Caspofungin
DownloadSpring 2015
Candida albicans is an opportunistic pathogen and major cause of invasive fungal infections. Choice of antifungal therapy is complicated by the underlying associated diseases of patients infected, other drug interactions, and in vitro susceptibility of the isolate. Echinocandins are emerging as a...
-
Fall 2011
ABSTRACT Wnt signalling is of great biological importance as it has been implicated in development and cancer. The Wnt canonical pathway (WCP) is the best characterized signalling pathway. Based on my preliminary studies in my first and second years I found that the WCP is not linear and that it...
-
Spring 2013
There has been significant interest in the literature on the possibility of using red blood cells (RBCs) derived from umbilical cord blood (cord RBCs) for neonatal transfusions. Low stability of cord RBCs during hypothermic storage necessitates the development of a cryopreservation method to...
-
Cytotoxicity, mutagenicity, and genotoxicity of emerging drinking water disinfection byproducts
DownloadSpring 2014
Drinking water disinfection byproducts (DBPs) are formed unintentionally when organic matter in raw water reacts with disinfectants used to kill pathogens. Epidemiological studies have shown that an increased risk of bladder cancer is associated with consumption of chlorinated water, but little...
-
Deletion or substitution of conserved amino acid residues at the tip of the domain IV of Tet(O) impairs tetracycline resistance
DownloadSpring 2011
Resistance to tetracycline (Tc), an inhibitor of protein synthesis, decreases its effectiveness for the treatment of bacterial infections. Tc resistance (TcR) can be mediated by the ribosomal protection protein, Tet(O), which was first reported in Campylobacter jejuni, a cause of bacterial...
-
Delineating the biology of Anaplastic Lymphoma Kinase (ALK) and its resistance to crizotinib
DownloadFall 2017
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase receptor that was initially identified as a potent oncogenic driver in anaplastic large-cell lymphoma (ALCL) in the form of NPM-ALK fusion protein. Various forms of oncogenic ALK proteins have been identified, subsequently, in various...
-
Delineation of Molecular Mechanisms Underlying the Pathobiology of ALK-positive Anaplastic Large-cell Lymphoma
DownloadSpring 2017
ALK-positive anaplastic large-cell lymphoma (ALK+ALCL) is a rare type non-Hodgkin lymphoma of null/T cell original, preferentially occurs in children and young adults. Approximately 85% of ALK+ALCL patients carry the gene translocation t(2;5)(p23;q35), which results in the generation of the...
-
Spring 2013
Chavali Venkata Subramanya, Ravi Shankar
The In-gel polymerase chain reaction (PCR) technology developed by our group at the University of Alberta makes use of PCR reagents entrapped within nano-liter polyacrylamide gels. To adapt this technology for use at the point of care, methods were developed to preserve gel-based PCR reagents by...
-
Design, Synthesis and Antimycobacterial Evaluation of a Novel Class of Chemotherapeutic Agents
DownloadFall 2017
Mycobacterium tuberculosis (Mtb), one of the deadliest known human pathogens, infects ~ 2 billion people (33% of the world's population) and remains the leading infectious cause of death. According to the World Health Organization's (WHO) report, 225 million new infections will occur and ~79...
-
Fall 2015
Reoviruses have been shown to infect a very broad range of mammalian sources and infections in humans have been associated with gastrointestinal and respiratory illnesses. While the presence of reovirus in several different water matrices and clinical samples has been reported, the clinical...