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Fall 2020
Adolescent idiopathic scoliosis (AIS) is a spinal disorder causing abnormal curvature of the spine in three dimensions (3D), starting in the patient’s adolescence, and having no known cause. Bracing is the most common non-surgical method of treating AIS, but the brace design is heavily reliant on...
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An ancestral role in de novo peroxisome assembly is retained by the divisional peroxin Pex11 in the yeast Yarrowia lipolytica
DownloadFall 2014
This thesis is on peroxisome evolution and reports my findings with regard to two major aspects of this process. First, I investigated the evolution of a peroxisomal protein family for which large expansions had been noted in diverse eukaryotes from a comparative genomic perspective and combined...
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Fall 2016
Gliomas, tumours arising from the glial cells of the nervous system, are some of the most difficult tumours to treat. In particular, glioblastoma are a particularly aggressive glioma subtype carrying a life expectancy of only 14 months. Typically, treatment combines surgery, radiation and...
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An Apparatus of (In)Difference: Governing Indigenous Food (In)Security through Healthism in Winnipeg, Manitoba
DownloadSpring 2021
Engaging with the fields of critical Indigenous theory, Indigenous STS (Science, Technology, and Society), and governmentality, An Apparatus of (In)Difference interrogates how Indigenous food insecurity policy reiterates food insecurity as a matter of poor health choices. I delineate how a...
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Fall 2011
Microarrays are biotechnological advancements measuring expressions of thousands of genes in a single assay. A two-group microarray study yields gene expression measurements for patients with a disease of interest and for healthy controls. Our objective is to apply the methods of microarray data...