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Experimental evaluation and model development for analysis of pressure drop in the lungs of children
DownloadFall 2018
Airway resistance describes the ratio between pressure drop and flow rate through the conducting respiratory airways. Analytical models of airway resistance for tracheobronchial airways have previously been developed and assessed without upper airways positioned upstream of the trachea. This...
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Improving Portable Oxygen Concentrator Performance through the development of a New Nasal Interface
DownloadFall 2021
Long term oxygen therapy (LTOT) is used to improve survival for patients with respiratory diseases who experience chronic respiratory failure. During LTOT, supplemental oxygen is supplied to patients from an oxygen source via cannula supply tubing. Portable oxygen concentrators (POCs) are a...
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Fall 2022
The objective of this thesis is to describe two new methodologies for evaluating medical gas and nasal spray delivery, respectively, in vitro using nasal replicas. The first half of the body of thesis describes the development of a new in vitro benchtop method for evaluating the delivery of...
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Spring 2023
It is common for face masks to be used in conditions that mask manufacturers did not intend, such as multiple donning of masks during supply shortage, but the mask performance in varying usage conditions are typically not regulated and assumed beneficial without the quantification of the actual...
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Quantifying and Correlating the Positive Airway Pressure and Upper Airway Gas Clearance During High Flow Nasal Cannula Therapy in Adults
DownloadSpring 2019
High flow nasal cannula (HFNC) therapy is a form of respiratory support, where high flowrates of heated and humidified gas are supplied to a patient via nasal cannula. This thesis consists of two experimental studies designed to characterize the positive pressure and upper airway washout effects...
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Fall 2018
The goal of this thesis work was to develop an idealized adult nasal airway geometry capably of mimicking average regional nasal deposition of droplets emitted from pharmaceutical nasal sprays. The first part of this thesis examined regional deposition within the nose for nasal sprays over a...