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- 1Antimicrobial
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- 1Cancer Nanomedicine
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Spring 2012
Gold and silver dressing alloys were created by DC magnetron sputtering and compared with pure silver nanocrystalline dressings using conventional biological and physical characterization techniques. While the gold/silver dressings were weaker antimicrobials than the pure silver nanocrystalline...
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Fall 2010
Abstract: Introduction: Partial bladder outlet obstruction (pBOO) is a ubiquitous problem that results in renal damage. We hypothesize that change in the bladder progresses over time. Methods: Fischer rats underwent surgical pBOO for 2, 4, 8, or 13 weeks and were compared to shams. Urodynamic...
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Development of A Gadolinium-Based Nanotheranostics Platform for Irradiation Activatable MRI-Radiosensitization and Doxorubicin Release in Cancer Therapy
DownloadSpring 2022
The ultimate goal of this thesis research was to design, fabricate, and characterize an integrated nanotheranostics platform for activatable doxorubicin delivery and simultaneous MRI- radiosensitization for synergistic cancer therapy, targeting breast cancer treatment. As shown in the diagram,...
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Nanocrystalline Silver and Silver-Gold Materials for Inflammation Reduction and Surgical Adhesion Prevention
DownloadFall 2024
Surgical adhesions are caused by tissue trauma and inflammation and present a high clinical burden. Nanocrystalline silver is known to be a strong anti-inflammatory and antibacterial material. This thesis explores the potential for nanocrystalline silver and silver-gold to be used to treat...
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Thin Film Point of Care Diagnostic and the Potential Mitigation of Antimicrobial Resistance
DownloadFall 2021
Antimicrobial resistance is an emerging worldwide threat that endangers the effectiveness of many of the gains of modern medicine. Therapies are becoming less effective through their overuse even while antimicrobial stewardship programs have been developed to measure and improve how antibiotics...