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Skip to Search Results- 36Field, Catherine J.
- 29Stothard, Paul
- 20Chan, Catherine B.
- 20Prado, Carla M.
- 19Proctor, Spencer D.
- 19Weselake, Randall J.
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Milk-derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) promote adipocyte differentiation and inhibit inflammation in 3T3-F442A cells
Download2015
Chakrabarti, Subhadeep, Wu, Jianping
Milk derived tripeptides IPP (Ile-Pro-Pro) and VPP (Val-Pro-Pro) have shown promise as anti-hypertensive agents due to their inhibitory effects on angiotensin converting enzyme (ACE). Due to the key inter-related roles of hypertension, chronic inflammation and insulin resistance in the...
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Minimally-invasive assessments of the behavioural and physiological effects of enriched colony cages on laying hens
Download2011
Korver, Doug R., Schaefer, Allan L., Cook, Nigel J., Feddes, John J. R., Church, John S., Haley, Derek B.
The well-being of laying hens in cages of 5, 10, 20 and 40-birds/cage, and enrichment with perches, nest boxes and scratch pads, was assessed using behavioral and physiological parameters. Laying hens were Lohmann Brown (n = 360) and White Leghorns (n = 360), housed from 17 to 65 weeks of age....
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2003
Chan, Catherine B., Wang, Xiaolin, Koshkin, Vasilij, Wheeler, Michael B., Scherer, Philipp E.
Excessive free fatty acid (FFA) exposure represents a potentially important diabetogenic condition that can impair insulin secretion from pancreatic β-cells. Because mitochondrial oxidative phosphorylation is a main link between glucose metabolism and insulin secretion, in the present work we...
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2014
Bamforth, Fiona, Stothard, Paul, Peng, Fred, Sergi, Consolato, Chan, Alicia, Bahitham, Wesam, Stone, Bradley, Mason, Andrew, Liao, Xiaoping
Cholangiocellular carcinoma (CCA) of the liver was the target of more interest, recently, due mainly to its increased incidence and possible association to new environmental factors. Somatic mitochondrial DNA (mtDNA) mutations have been found in several cancers. Some of these malignancies contain...
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Molecular targets of antihypertensive peptides: Understanding the mechanisms of action based on the pathophysiology of hypertension
Download2015
Majumder, Kaustav, Wu, Jianping
There is growing interest in using functional foods or nutraceuticals for the prevention and treatment of hypertension or high blood pressure. Although numerous preventive and therapeutic pharmacological interventions are available on the market, unfortunately, many patients still suffer from...
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Morphological characterization of fungi associated with the ascochyta blight complex and pathogenic variability of Mycosphaerella pinodes on field pea crops in central Alberta
Download2015
Gossen, Bruce, Strelkov, Stephen, Ahmed, Hafiz, Hwang, Sheau-Fang, Zhou, Qixing, Conner, Robert, Chang, Kan-Fan, Fu, Heting
Field pea crops in central Alberta were surveyed for ascochyta blight from 2011 to 2012 and fungal isolates were recovered from foliar lesions on selected plants. Cultural and microscopic characterization of the 275 isolates obtained revealed that 272 were of Mycosphaerella pinodes and three were...
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Multiple mechanisms contribute to increased neutral lipid accumulation in yeast producing recombinant variants of plant diacylglycerol acyltransferase 1
Download2017-09-01
Shah, Saleh, Xu, Yang, Ramakrishnan, Geetha, Caldo, Kristian Mark P., Chen, Guanqun, Ozga, Jocelyn, Greer, Michael S., Lemieux, M. Joanne, Wu, Limin, Weselake, Randall J.
The apparent bottleneck in the accumulation of oil during seed development in some oleaginous plant species is the formation of triacylglycerol (TAG) by the acyl-CoA-dependent acylation of sn-1,2- diacylglycerol catalyzed by diacylglycerol acyltransferase (DGAT, EC 2.3.1.20). Improving DGAT...
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n-3 fatty acids inhibit transcription of human IL-13: Implications for development of T helper type 2 immune responses
Download2013
Cameron, Lisa, Madsen, Norman, MacLean, Emily, Vliagoftis, Harissios, Field, Catherine J.
Fish oil supplementation during pregnancy has been associated with lower levels of cord blood IL-13, suggesting that the administration of n-3 fatty acids may attenuate the development of allergic disease. The present study aimed to investigate the mechanism by which n-3 fatty acid administration...
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Necrotic enteritis potential in a model system using Clostridium perfringens isolated from field outbreaks
Download2007
Bruce, Heather L., Boerlin, Patrick, Barnum, Donald A., Toole, Denise L., Chalmers, Gabhan
Necrotic enteritis is an enteric disease of avian species caused by the anaerobic bacterium Clostridium perfringens. The disease is regularly controlled in the broiler chicken industry with antimicrobials in feed but is reemerging in areas such as Europe where there is a ban on antimicrobials as...
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Neutrophil elastase alters the murine gut mirobiota resulting in enhanced Salmonella colonization
Download2012
Hartmann, Martin, Sekirov, Inna, Finlay, B. Brett, Al-Zahrani, Fatimah, Willing, Benjamin P., Ferreira, Rosana B. R., Gill, Navkiran, Antunes, L. Caetano M.
The intestinal microbiota has been found to play a central role in the colonization of Salmonella enterica serovar Typhimurium in the gastrointestinal tract. In this study, we present a novel process through which Salmonella benefit from inflammatory induced changes in the microbiota in order to...