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Spring 2023

Wu, Simon Si Zhe

Background Peripheral nerve injury is common, effecting 3% of the population. While surgery can be effective in moderate cases, complete neurologic and functional recovery are often not possible in severe cases of proximal nerve injury. Poor outcomes are attributable to the long-distance nerves...

Spring 2024

Lavoie, Ewen

Virtual Reality (VR) has emerged as a powerful tool for investigating human perception, cognition, and behavior. The ability to create immersive and interactive environments provides researchers with the opportunity to study human behavior in controlled and repeatable conditions. In recent years,...

Spring 2024

Gupta, Somnath

Recovery after stroke depends on the extent of neuronal regeneration and myelination of existing and newly differentiated neurons. Regeneration process is governed by various factors released from glial cells. During an injury, glial cells activate and form a glial scar surrounding the lesion...

Fall 2018

Mifflin, Katherine A

Sex traditionally has been an understudied variable in the chronic pain literature. However, more recent research has begun to explore the role of sex in the etiology of chronic pain. The present thesis adds to the current literature by expanding on research demonstrating the significant effect...

Fall 2021

Ouellette Zuk, Alexandra A.

As decisions require actions to have an effect on the world (Cisek & Kalaska, 2010), measures derived from movements can be used to provide a powerful index of decision-making processes (e.g., Gallivan & Chapman, 2014). Measures of trajectory curvature (interpreted as a competitive pull from the...

Fall 2024

Leverett, Jessica A.

How do you know your hand is moving without looking at it? This “movement sense”, known as kinesthesia, is thought to be primarily informed by receptors in muscles; specifically, the muscle spindles. As we move, muscle spindles discharge when muscles lengthen and, thus, most research has focussed...

Spring 2023

Budd, Alexandra

Parkinson’s disease (PD) is the second most common neurodegenerative disorder and causes not only well-characterised motor symptoms, but also a host of non-motor symptoms that greatly impact quality of life. PD exists within a larger spectrum of disorders caused by the accumulation of Lewy bodies...

Fall 2019

Junqiang, Ma

Ischemic stroke is caused by blockage of a primary blood vessel supplying brain tissue. Cerebral collaterals are auxiliary vascular pathways in the cerebral circulation that can provide residual blood flow to partially maintain perfusion in ischemic tissue when primary vascular routes are...

Spring 2019

Caballero, Hebert S

In aging, executive function (EF) performance (level) and change (trajectory) are linked to multiple interacting risk factors. Structurally, EFs have previously been represented as either a unitary (e.g., unidimensional) or diverse (e.g., multidimensional) set of abilities that change across the...

Fall 2018

Velanki, Hemalatha

The goal of this study was to investigate the effects and mechanisms of action of an intermittent electrical stimulation (IES) paradigm on the healing of deep-seated muscle injury. Electrical stimulation has been extensively studied for the treatment of open wounds, often with amplitudes lower...