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Skip to Search Results- 1Abdualmjid,Reem J
- 1Alhhazmi, Areej
- 1Alqahtani,Hind M
- 1Alshalani, Abdulrahman
- 1Alyenbaawi, Hadeel Eb
- 1Blackstock, Lindsay K.
- 3Tyrrell, Gregory (Laboratory Medicine and Pathology)
- 2Acker, Jason (Laboratory Medicine and Pathology)
- 2Li, Xing-Fang (Laboratory Medicine and Pathology)
- 1Bamforth, Fiona (Co-supervisor, Department of Laboratory Medicine & Pathology)
- 1Charlton, Carmen (Laboratory Medicine and Pathology)
- 1Damaraju, Sambasivarao (Laboratory Medicine and Pathology)
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Assessing the N-Nitrosamine Formation Potential of Selected Ionic Liquids, 1-Ethyl-3-Methylimidazolium Bromide and 1-Ethyl-1-Methylpyrrolidinium Bromide, Treated With the Drinking Water Disinfectant Monochloramine
DownloadSpring 2019
Ionic liquids (ILs) are increasingly used in industrial processes as “green chemicals” because of unique properties of low volatility and customizability. ILs can be used to enable novel processes and/or replace conventional organic solvents in a wide variety of applications. Widespread use may...
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DDX17 (P72), a Sox2 binding partner, regulates Sox2 to sustain tumorigenic and stem-like properties in a phenotypically distinct subset of estrogen positive breast cancer cells
DownloadSpring 2016
Abstract: Sox2, an embryonic stem cell marker, is involved in the pathogenesis of breast cancer (BC). Sox2 expression is associated with a poor clinical outcome in BC patients. Based on the differential Sox2 transcriptional activity, we have identified the two phenotypically distinct cell...
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Fall 2014
The vast majority of anaplastic lymphoma kinase positive anaplastic large cell lymphoma (ALK+ALCL) tumors carry the genetic translocation t(2;5)(p23;q35), leading to production of the constitutively active fusion tyrosine kinase NPM-ALK. NPM-ALK expression and its potent transformative properties...
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Developing a cryopreservation protocol for human umbilical vein endothelial cells (HUVECs) in monolayers
DownloadFall 2017
Cryopreservation is a process by which biological materials (cells and tissues) are cooled down to cryogenic temperatures (such as the temperature of liquid nitrogen –196 °C), are maintained at this temperature for a long period of time and then thawed to resume their normal functions [1]. At...
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Development of immuno-affinity mass spectrometry assays for the detection and quantification of viral antigens and antibodies
DownloadFall 2022
Currently, immunoassays are the gold standard tools for the detection and measurement of proteins in biological samples. These methods have a high level of sensitivity but are prone to limitations, such as non-specific binding and limited specificity due to cross-reactivity. This research aimed...
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Distribution Dynamics of Biologically Aged RBC Subpopulations: Impact of Blood Component Manufacturing Methods, Cryopreservation, and Irradiation
DownloadFall 2024
The quality of red blood cell concentrates (RCCs) is influenced by storage duration, donor variability, and processing methods. RCCs contain heterogeneous subpopulations of red blood cells (RBCs), ranging from young (Y-RBC) to old (O-RBC), each with distinct structural and biochemical...
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Fall 2016
Water disinfection inactivates microbiological pathogens in drinking water but also unintentionally produces disinfection byproducts (DBPs). Epidemiological studies have observed potential correlations between the consumption of chlorinated water with an increased risk of developing bladder...
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Spring 2020
Group B Streptococci (GBS) is the leading cause of invasive diseases in neonates, pregnant women and non-pregnant adult. In order to cause invasive disease, GBS encodes several virulence factors that are involved in the disease process. One such factor is the moonlighting glycolytic enzyme,...
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Group A Streptococcus (GAS): its surface phosphoglycerate kinase (PGK) and recent epidemiology in Alberta
DownloadFall 2017
Streptococcus pyogenes, also known as Group A Streptococcus (GAS) is a bacterium that causes diseases such as pharyngitis, acute rheumatic fever and invasive disease. In Alberta, the invasive GAS incidence rate has increased from 4.77/100 000 (2010) to 7.69/100 000 (2016). GAS emm 1 and 59 were...
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Identification and Characterization of a Novel Premenopausal Breast Cancer Locus and Insights into Copy Number Variations for Disease Predisposition and Prognosis
DownloadFall 2018
Breast cancer is a complex multifactorial disease with the interplay of genetic, environmental and lifestyle factors contributing to the disease risk. Studies based on twins estimated that ~30% of the risk is due to genetic factors. High and moderate penetrant mutations along with low penetrance...