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Fall 2016

Shao, Wenjie

Chapter 1 describes a general route for making 1,3'-bipyrroles. This work involves intermolecular conjugate displacement using a special Michael acceptor developed in this laboratory. This method is general and enables the construction of highly substituted 1,3'-bipyrroles. The route was first...

Spring 2016

Shearer, Lindsay J

Nanomaterials have gained interest due to their unique physical and chemical phenomena that is only observed for materials in this size regime. In the biohealth sector, gold nanoparticles are good platforms for use in curative treatments and detection of cancer and disease. However, their...

Spring 2016

Li, Zhendong

The simultaneous quantification of all biological molecules, from metabolites to proteins, holds the key to discovering molecular signatures that can diagnose diseases before irreversible damages have occurred in the body. Recent advances in the field of liquid chromatography coupled mass...

Spring 2016

Kwok, Samantha, P

A unique borylative migration of heterocyclic enol perfluorosulfonates has been developed to access six-membered heterocyclic α-substituted allylboronates in a stereoselective and efficient manner. The synthetic utility of the allylboronate intermediates was demonstrated by a highly...

Spring 2016

Niu, Tianmin

Metallocarbenes, in situ generated from catalytic decomposition of diazocarbonyl compounds, contain only 6 electrons at carbon center, therefore are highly electrophilic. Over the years, the metallocarbene intermediates have been continuously explored as a versatile tool toward C-C and C-X bond...

Spring 2016

Cochrane, Rachel V K

Cladosporin is a polyketide metabolite that is biosynthesized by a highly reducing (HR)/non-reducing (NR) polyketide synthase (PKS) pair, wherein they catalyse head-totail condensation of acetyl and malonyl CoA units with subsequent β-keto modification. Cladosporin has recently been reported as a...

Fall 2016

Ramachandran, Krishna Kumar

Several series of rare-earth and transition-metal-containing pnictides such as RE2Mn3Cu9Pn7,1 REMnCu4P3,2 REMM'Pn2 (M = Mn, Cu, Ag; M' = Cu, Zn, Cd; Pn = P, As),3 and REAg1-xZnyAs2 4 were synthesized, and their crystal structures were determined using X-ray diffraction methods. The electronic...

Spring 2016

Hadidi, Lida

Nanomaterials are important building blocks of nanotechnology. Their size dependent unique properties (optical, magnetic, electrical, etc.) have the potential to revolutionize applications ranging from medicine to electronics. Of the various nanomaterials, carbon-based systems including porous...

Spring 2016

Kaufman, Gregory J

Cellulose nanocrystals (CNC) are an emerging green nanomaterial with a unique property set that permits its use to enhance traditional materials in various ways. One of the main focuses has been to impart the incredible mechanical stiffness of these nano particles into conventional thermoplastic...

Spring 2016

Zhang, Junfeng

Carbohydrates, an essential class of biomolecules, mediate a variety of biological processes. Recent advances in chemical, enzymatic and chemo-enzymatic synthesis have facilitated access to an increasing number of structurally well-defined oligosaccharides. These molecules are serving as...