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Skip to Search Results- 33Mass-spectrometry
- 24Chemistry
- 23Organic compounds. Synthesis.
- 22Metabolomics
- 21Capillary electrophoresis.
- 21Catalysis
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Spring 2016
Carbohydrates play vital roles in many disease pathologies, including inflammatory disease, cancer metastasis, autoimmune disease and pathogenic infection. Despite their significance and immense opportunity for pharmaceutical application, carbohydrate-derived drugs only constitute a relatively...
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Fall 2019
This thesis focuses on the development and application of electrospray ionization mass spectrometry (ESI-MS) based methods for characterizing glycoproteins (GPs) and investigating their interactions with glycan binding proteins (GBPs) and drugs. A multipronged approach was developed to identify...
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Spring 2019
Glycosphingolipids (GSLs) are a class of glycolipids characterized by two major components; an oligosaccharide chain and a ceramide lipid chain bearing a fatty acid and a sphingosine (Sph) base. Gangliosides belong to the family of GSLs whose distinguishing feature is the presence of one or more...
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Graphitic carbon phases for chelation chromatography and electrochemically modulated preconcentration
DownloadSpring 2012
The first part of this thesis explores the synthetic method that converts carbon clad zirconia particles into chelation stationary phase. Oxine groups were attached onto the graphitic carbon surface by in situ generated diazonium ions in the aqueous solution. XPS, FTIR, SEM were utilized to...
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Greener Chemistry Using Boronic Acids as Organocatalysts and Stoichiometric Reaction Promoters
DownloadFall 2012
Catalysis is crucial for society in view of producing pharmaceutical agents and commodity chemicals. Industry and academia alike are constantly searching for organic transformations which can not only efficiently produce important pharmaceuticals and commodity chemicals, but can also do so in a...