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Skip to Search Results- 1Abeysundara, Namal W
- 1Arnold, Kirsten J
- 1Barua, Moumita
- 1Buck, Melissa
- 1Konvalinka, Ana
- 1Leung, Albert Chun Cheung
- 5Graduate and Postdoctoral Studies (GPS), Faculty of
- 5Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 1Modern Languages and Cultural Studies, Department of
- 1Modern Languages and Cultural Studies, Department of/Research Materials (Modern Languages and Cultural Studies)
- 1Nursing, Faculty of
- 1Nursing, Faculty of/Chronicity
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Characterisation of novel potential phosphorylation sites in the tumour suppressor Merlin in Drosophila
DownloadFall 2014
Neurofibromatosis Type II is an inherited cancer that manifests as various tumours in the nervous system. Mutations and deletions in the tumour suppressor Merlin (moesin, ezrin, radixin-like protein) are linked to the development of the disease. The mechanism by which Merlin suppresses cell...
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Characterisation of the Non-Canonical Translation Initiation Factor eIF4E-3 as a Merlin Interacting Protein in Drosophila melanogaster
DownloadSpring 2016
Merlin is a tumour suppressor protein, the loss of which is linked to the inherited nervous system tumour syndrome Neurofibromatosis type 2 as well as sporadic tumour development. It is related to the ERM (ezrin-radixin-moesin) protein family, which is involved in linking the cytoskeleton to...
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Fall 2017
Merlin and the ezrin-radixin-moesin (ERM) proteins are key organizers of the cell cortex through linking membrane-associated proteins to the underlying actin cytoskeleton. Merlin and the ERM proteins have been implicated in the maintenance of cell integrity, adhesion, and motility during tissue...
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Flapwing Dephosphorylates Merlin and Moesin and Regulates Epithelial Integrity in Drosophila
DownloadFall 2013
Merlin is a tumor suppressor protein whose inactivation is associated with familial Neurofibromatosis Type II (NF2) and other sporadic tumors. The growth-suppressive function of Merlin is modulated by reversible phosphorylation. Our previous finding showed the Sterile20 kinase Slik coordinately...
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2017-08-22
Molnar, Amber O., Barua, Moumita, Konvalinka, Ana, Schick-Makaroff, Kara
Purpose of Review: Patient engagement in research is increasingly recognized as an important component of the research process and may facilitate translation of research findings. To heighten awareness on this important topic, this review presents opportunities and challenges of patient...
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2020-08-01
This is a transcription of Paul Mascarene’s eighteenth-century translation of Molière’s Le Misanthrope, based on an undated and untitled manuscript that is bound in a volume with other records from Mascarene’s time as a military and civic leader in British Nova Scotia, held in the British...
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Fall 2011
Mutations in the NF2 gene lead to the disease Neurofibromatosis Type II which is characterized by the formation of multiple tumours in the central nervous system. The NF2 gene encodes the protein Merlin. Merlin interacts with a number of different proteins and these interactions may be important...
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2016-04-15
This thesis examines how the Hebrew word רוח is used in Ezekiel 37:1-14 and the Greek word πνευμα is used in John 3:1-21. Greek and Hebrew are two very different languages. Yet they often are paired together, since they are the two main languages used in the Christian Bible. They certainly have...