This decommissioned ERA site remains active temporarily to support our final migration steps to https://ualberta.scholaris.ca, ERA's new home. All new collections and items, including Spring 2025 theses, are at that site. For assistance, please contact erahelp@ualberta.ca.
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Fall 2021
Terahertz (THz) radiation is a non-ionizing form of electromagnetic (EM) energy that occupies a broad frequency region at the interface between conventional microwave and infrared bands. The strong coupling between THz excitations and natural oscillatory dynamics in biological systems has...
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Colorectal Cancer Small Extracellular Vesicles Induce Matrix Metalloproteinase Expression, an Invasion-Promoting Phenotype, and CD147-Dependent MAPK/AP-1 Activation in Macrophages
DownloadFall 2020
Exosomes and small microvesicles are types of small extracellular vesicle (sEVs) secreted by cancerous and normal cells. sEVs are filled with cargo from cancer cells that may affect both nearby and distant tissues. sEVs from colorectal cancers that enter blood vessels draining the intestine will...
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Novel radiation-activated Photodynamic Therapy (radioPDT) Theranostic Nanoparticle for Treatment of Deep-seated Tumors
DownloadSpring 2020
Radiotherapy is used in the treatment of 50% of all cancer patients. It has evolved into a high precision therapy in cancer care. Radiotherapy’s main limitation is the damage incurred on normal tissue. Advances in modern radiotherapy allowed for improved precision in delivery and optimizes its...
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The lysosomotropic agent siramesine induces cell death in prostate cancer cells and synergizes with the tyrosine kinase inhibitor lapatinib
DownloadFall 2024
Prostate cancer is the most diagnosed cancer affecting Canadian men. Prostate tumors that progress from localized disease to advanced stages show resistance to standard therapy, a major problem that requires alternative treatments. One new treatment possibility is targeting lysosomal membrane...
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Spring 2024
DNA double-strand breaks (DSBs) are considered the most deleterious DNA lesions. Unrepaired or incorrectly repaired DSBs can lead to cell cycle arrest, apoptosis, or over time, the accumulation of mutations and chromosomal abnormalities that give rise to cancer. The repair of DSBs by homologous...