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Evaluating the Role of Bacterial Lipopolysaccharide on Etiology and Pathogenesis of Transmissible Spongiform Encephalopathies
DownloadFall 2014
Transmissible spongiform encephalopathies (TSEs) or otherwise known as prion diseases are a class of fatal neurodegenerative diseases related to irreversible brain damage. Presently, there is no effective treatment or preventive strategy for this disease because the etiology and biological...
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Lipidomics of Biological Samples for the Assessment of Physiological and Pathological Processes
DownloadFall 2020
Lipids are a large class of hydrophobic molecules involved in energy storage, signaling, modulation of gene expression and membranes. Lipidomics focuses on the comprehensive analysis of lipids and their interactions. Although the potential of lipidomics to study physiological and pathological...
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Putative ante-mortem indicators of Alzheimer’s dementia: Analysis of fluid biomarker and neuroimaging studies
DownloadSpring 2019
Dementia is a clinical state, characterized by symptoms indicative of deterioration of memoryand cognitive functions that interferes with social or occupational functioning. According to2018 statistics, around 50 million people are living with dementia, and this number will increaseto 131.5...