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- 1Association study
- 1Body mass index
- 1Breast cancer
- 1Copy neutral-loss of heterozygosity
Breast cancer is the most common cancer among women in the developed world. The disease results from the combined effects of genetic, environmental, reproductive and lifestyle risk factors. Germline DNA variations identified thus far by linkage and genome-wide association studies (GWASs) account...
Speciation can be an elaborate process. Delimiting species and reconstructing evolutionary relationships may be similarly complex, revealing gene tree discordance, cryptic species, geographic structuring or hybridization. In order to solve such systematic problems, a careful balance should be...
Previous studies of the grey wolf (Canis lupus) using microsatellites have showed strong population structure despite the high mobility of individuals. I re-assessed the structure of North American grey wolves by genotyping 132 wolves at a genome-wide set of >26 000 single nucleotide...
Traditionally, population delineation has been determined using mark-recapture, band returns, and more recently, telemetry, geologgers and genetics. But telemetric and genetic population structure data have rarely been examined concurrently to explore differences and similarities. I define a...
O'Sullivan, N.P., Wong, G.K., Lawley, C.T., McKay, J.C., Groenen, M.A., Fulton, J.E., Crooijmans, R.P., Muir, W.M., Megens, H.J., Cheng, H.H., McLeod, S., Zhang, H.M., Zhang, Y., Albers, G.A.A., Delany, M.E., Settar, P., Okimoto, R., Vereijken, A., Wang, J., Jungerius-Rattink, A.
In 2004 the chicken genome sequence and more than 2.8 million single nucleotide polymorphisms (SNPs) were reported. This information greatly enhanced the ability of poultry scientists to understand chicken biology, especially with respect to identification of quantitative trait loci (QTL) and...