SearchSkip to Search Results
- 1Arcuate Nucleus
- 1Bcl, Ki67, P53, P16, EGFR.
- 1Calcium Imaging
Characterization of Human Pancreatic Beta-cell Progenitors as a Means to Alleviate the Shortage of Donor Tissue for Islet TransplantationDownload
The current shortage of islet tissue from cadaveric human donors is not sustainable and will preclude islet transplantation from becoming a widespread therapeutic treatment for those with type 1 diabetes. A potential alternative source of tissue may be through isolating, expanding, and...
An individual’s body weight is tightly regulated by balancing food intake with energy expenditure. This is accomplished in part by secretion of the hormone leptin by adipocytes, an excess of which signals to reduce appetite and increase activity through action in the hypothalamic region of the...
Fibre-Type Specific Nuclear Localisation Patterns of NFAT-isoforms in CLFS Induced Skeletal Muscle AdaptationsDownload
The purpose of this investigation was to characterize the nuclear localisation patterns of NFAT-c1, -c2, -c3, and -c4 in relation to chronic low-frequency stimulation induced fibre type transitions. A model has been suggested to describe the roles of all 4 NFAT isoforms in activity-dependent...
AimsOral cavity squamous cell carcinoma (OCSCC) is a molecularly heterogeneous disease, which is thought to account for differences in treatment response between patients who have otherwise similar characteristics. Cancer biomarkers provide a means of molecular classification, which can be of...