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Fall 2016

Swan, Amanda C

Gliomas, tumours arising from the glial cells of the nervous system, are some of the most difficult tumours to treat. In particular, glioblastoma are a particularly aggressive glioma subtype carrying a life expectancy of only 14 months. Typically, treatment combines surgery, radiation and...

Spring 2017

Fung, Rachel D

Gliomas are the most common primary malignant brain tumour in adults, with glioblastoma multiforme (GBM), the most common and most deadly form of glioma, making up over half of all diagnosed cancers in the brain/central nervous system. The standard of care for gliomas has remained unchanged for...

Fall 2022

Hall, Meghan

From the mechanical processes that produce the convolutions in the human brain needed for complex thought, to the precise and controlled movements derived by intuitive calculations of body position in figure skating, mechanics plays a role in everything we do. In this thesis, we apply and examine...

Fall 2012

Beaulieu, Michael J.

Malignant gliomas (MG) are the most common and aggressive brain cancers. FABP7 is an intracellular lipid trafficking molecule whose expression correlates with reduced MG patient survival. FABP7 has been shown to increase the migratory behaviour of MG cells. Moreover, the migratory behaviour of...

Fall 2010

Mita, Raja

Patients diagnosed with malignant glioma tumours have median survivals of 1.6 yrs and 5 months, respectively, highlighting the deadly nature of this disease. Despite aggressive multimodal treatment, patients with malignant glioma often present with secondary brain tumours at sites distal to the...