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Skip to Search Results- 28Graduate and Postdoctoral Studies (GPS), Faculty of
- 28Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 13Agricultural, Food and Nutritional Science, Department of
- 13Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 12Biological Sciences, Department of
- 12Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 10Department of Agricultural, Food, and Nutritional Science
- 3Department of Biological Sciences
- 2Department of Computing Science
- 2Department of Oncology
- 2Medical Sciences-Laboratory Medicine and Pathology
- 1Department of Cell Biology
- 2Baracos, Vickie (Oncology)
- 2Damaraju, Sambasivarao (Laboratory Medicine and Pathology)
- 2Putman, Charles (Physical Education and Recreation)
- 1Ali, Declan W. (Biological Sciences)
- 1Baracos, Vickie (Oncology & Agricultural, Food, and Nutritional Science)
- 1Belosevic, Miodrag (Biological Sciences)
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Fall 2014
The purpose of this work is to understand properties of skeletal muscle of cancer patients experiencing severe muscle depletion. These studies were done using computed tomography (CT) imaging and patient information (demographics), and collection of muscle biopsies to analyze using flow...
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Spatiotemporal integration of molecular and anatomical data in virtual reality using semantic mapping
Download2009
Janzen, R.P., Dong, X., Gordon, P.M., Soh, J., Wishart, D.S., Sabhaney, A., Turinsky, A.L., Sensen, C.W., Chang, J., Hau, D., Xia, J., Trinh, Q.M.
We have developed a computational framework for spatiotemporal integration of molecular and anatomical datasets in a virtual reality environment. Using two case studies involving gene expression data and pharmacokinetic data, respectively, we demonstrate how existing knowledge bases for molecular...
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Fall 2013
Cancer cachexia is a multifactorial syndrome characterized by involuntary weight loss, wasting of skeletal muscle driven by reduced food intake and abnormal metabolism. Cachexia has a negative impact on quality of life, response to chemotherapy and survival. Cachexia research is undeveloped with...
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Spring 2017
Survival prediction is becoming a crucial part of treatment planning for most terminally ill patients. Many believe that genomic data will enable us to better estimate survival of these patients, which will lead to better, more personalized treatment options and patient care. As standard...
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T cell-mediated inflammation is stereotyped: mouse delayed-type hypersensitivity reaction and mouse T cell-mediated rejection of renal allografts share common molecular mechanismsT cell-mediated inflammation is stereotyped
DownloadFall 2011
Genome-wide gene expression analysis of diseases has revealed large-scale changes in the expression of thousands of genes (transcripts) representing biological processes. The processes that occur during T cell-mediated rejection (TCMR) of renal allografts in mice and humans have been previously...
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The biology and characterization of NOD-like receptors in goldfish (Carassius auratus L.) macrophages exposed to bacterial pathogens
DownloadSpring 2017
The recognition of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs) is important for the initiation of the host defense against pathogens. NOD-like receptors (NLRs) are a family of PRRs that primarily detect the cytosolic PAMPs of the pathogens. The NLRs have...
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The construction and use of bacterial DNA microarrays based on an optimized two-stage PCR strategy
Download2003
Li, H., Klahn, J., Galbraith, D.W., Deyholos, M., Sherman, L.A., Impson, L., Postier, B.L., Risinger, G., Andrews, H.L., Burnap, R.L., Pesta, D., Wang, H.L., Singh, A.
Background: DNA microarrays are a powerful tool with important applications such as global gene expression profiling. Construction of bacterial DNA microarrays from genomic sequence data using a two-stage PCR amplification approach for the production of arrayed DNA is attractive because it...
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The effects of intermittent suckling protocols on reproductive performance in primiparous sows
DownloadFall 2017
In pig production, sow reproductive efficiency is a key contributor to breeding herd productivity. A major challenge in the implementation of alternative sow housing and piglet management systems is the maintenance of production efficiency. Conventionally, sows are only bred once they come into...
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The mechanism of endothelial cell specific gene expression of Von Willebrand Factor in vivo
DownloadSpring 2010
In vivo analyses of the Von Willebrand Factor (VWF) promoter previously demonstrated that a fragment spanning sequences -487 to +247 targets promoter activation to brain vascular endothelial cells. This fragment is active in all embryonic vessels of transgenic mice but in adult mice its activity...
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The role of water channel proteins in facilitating recovery of leaf hydraulic concutance from water stress in Populus trichocarpa
Download2014
Gas exchange is constrained by the whole-plant hydraulic conductance (Kplant). Leaves account for an important fraction of Kplant and may therefore represent a major determinant of plant productivity. Leaf hydraulic conductance (Kleaf) decreases with increasing water stress, which is due to xylem...