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- 2Chan, Catherine B.
- 1Aalhus, Jennifer L.
- 1Beaudoin, Marie-Soleil
- 1Block, Hushton C.
- 1Cameron, Ashley C.
- 1Castellani, Laura
Expression of PPARα modifies fatty acid effects on insulin secretion in uncoupling protein-2 knockout miceDownload
Aims/hypothesis In uncoupling protein-2 (UCP2) knockout (KO) mice, protection of beta cells from fatty acid exposure is dependent upon transcriptional events mediated by peroxisome proliferator-activated receptor-α (PPARα). Methods PPARα expression was reduced in isolated islets from UCP2KO and...
Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seedDownload
Background Sea buckthorn (Hippophae rhamnoides L.) is a hardy, fruit-producing plant known historically for its medicinal and nutraceutical properties. The most recognized product of sea buckthorn is its fruit oil, composed of seed oil that is rich in essential fatty acids, linoleic (18∶2ω-6) and...
Beef fatty acid (FA) composition has emerged as a trait of economic importance as consumers have become more aware of the relationship between diet and health. As a result, they are paying more attention on the health impact of the food they consume including the type of dietary fat. Clinical...
Background Glyceroneogenesis is an important step in the control of fatty acid re-esterification with PEPCK and PDK4 being identified as key enzymes in this process. We have previously shown that glyceroneogenic enzymes such as PDK4 are rapidly induced in white adipose tissue during exercise....
Improving beef hamburger quality and fatty acid profiles through dietary manipulation and exploitation of fat depot heterogeneityDownload
Background Hamburger is the most consumed beef product in North America, but lacks in nutritional appeal due to its high fat content and high proportion of saturated fatty acids (SFA). Objectives of the present study were to improve the FA profiles of hamburgers made with perirenal fat (PRF) and...
The causes and etiology of Crohn's disease (CD) are currently unknown although both host genetics and environmental factors play a role. Here we used non-targeted metabolic profiling to determine the contribution of metabolites produced by the gut microbiota towards disease status of the host....
Responses to n-3 fatty acid (LCPUFA) supplementation of gestating gilts, and lactating and weaned sowsDownload
Feeding n-3 long-chain polyunsaturated fatty acids (LCPUFA) to gilts or sows has shown different responses to litter growth, pre-weaning mortality and subsequent reproductive performance of the sow. Two hypotheses were tested: (1) that feeding a marine oil-based supplement rich in protected n-3...
Attention Deficit/Hyperactivity Disorder (AD/HD) is the most prevalent paediatric neurodevelopmental disorder. Research implicates a deficiency of docosahexaenoic acid (DHA) in the aetiology of AD/HD. Supplementation with DHA may improve symptoms of AD/HD in children diagnosed with the...