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Skip to Search Results- 22Metabolomics
- 11Mass-spectrometry
- 6Chemical isotope labeling
- 5LC-MS
- 3Dansylation
- 3Electrospray ionization
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Metabolomics by GC×GC-TOFMS: Overcoming Challenges from Sample Preparation to Data Analysis Towards Standardization of the Workflow
DownloadSpring 2021
Metabolomics is an ‘omics’ field, which involves the comprehensive characterization of metabolites using analytical chemistry technologies and statistical methods to interpret the results. The term metabolomics was coined about two decades ago as an analogy to other precedent omics approaches:...
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Spring 2022
Metabolomics, as an interdisciplinary research area, requires the integration of knowledge from different disciplines, such as analytical chemistry, bioinformatics, and statistics. The general workflow of metabolome analysis includes sample preparation, data acquisition, data processing, data...
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Method Development of Chemical Isotope Labeling of Cellular Extract and Biofluids on Metabolomics Profiling and Its Application for Disease Biomarker Discovery
DownloadFall 2019
Metabolomics aims at studying all the small molecules in biological samples. Compared to transcriptome and proteome, metabolome is highly sensitive to diverse individuals and environmental factors. Thus, metabolomics study has been used to understand individual variations caused by genes,...
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Quantitative Characterization of Noncovalent Protein-Carbohydrate Interactions using Electrospray Ionization Mass Spectrometry
DownloadFall 2015
The interactions between water-soluble proteins and carbohydrates found on the surfaces of cells play important roles in many physiological and pathological cellular processes. Carbohydrates function as receptors for signaling, cellular recognition and adhesion, and pathogen infections. This...
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Separation and characterization of polycyclic aromatic hydrocarbons and azaarenes using normal phase liquid chromatography and electrospray ionization mass spectrometry
DownloadFall 2016
Normal phase liquid chromatography (NPLC) is widely used for separating petroleum into compound classes, such as polycyclic aromatic hydrocarbons (PAHs) and polar nitrogen containing compounds. The charge-transfer and hypercrosslinked polystyrene NPLC phases provide unique selectivities for PAHs....