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Skip to Search Results- 8Graduate and Postdoctoral Studies (GPS), Faculty of
- 8Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 1Toolkit for Grant Success
- 1Toolkit for Grant Success/Successful Grants (Toolkit for Grant Success)
- 1Modern Languages and Cultural Studies, Department of
- 1Modern Languages and Cultural Studies, Department of/Research Materials (Modern Languages and Cultural Studies)
- 2Hughes, Sarah (Medical Genetics)
- 1Ali A. Abdi, Department of Educational Policy Studies
- 1Hughes, Sarah (Department of Medical Genetics, Department of Cell Biology)
- 1Hughes, Sarah (Medical Genetics, Cell Biology)
- 1Hughes, Sarah C (Medical Genetics, Cell Biology)
- 1Lemire, Beverly (History and Classics)
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2016-10-13
SSHRC Awarded IG 2017: The importance of the body in fashion and the radical adoption of street styles by the elite go back to eighteenth-century Europe. This study examines the effects of the French Revolution on European and American style. It asks how 1790s fashion drastically changed to...
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Characterisation of novel potential phosphorylation sites in the tumour suppressor Merlin in Drosophila
DownloadFall 2014
Neurofibromatosis Type II is an inherited cancer that manifests as various tumours in the nervous system. Mutations and deletions in the tumour suppressor Merlin (moesin, ezrin, radixin-like protein) are linked to the development of the disease. The mechanism by which Merlin suppresses cell...
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Characterisation of the Non-Canonical Translation Initiation Factor eIF4E-3 as a Merlin Interacting Protein in Drosophila melanogaster
DownloadSpring 2016
Merlin is a tumour suppressor protein, the loss of which is linked to the inherited nervous system tumour syndrome Neurofibromatosis type 2 as well as sporadic tumour development. It is related to the ERM (ezrin-radixin-moesin) protein family, which is involved in linking the cytoskeleton to...
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Fall 2017
Merlin and the ezrin-radixin-moesin (ERM) proteins are key organizers of the cell cortex through linking membrane-associated proteins to the underlying actin cytoskeleton. Merlin and the ERM proteins have been implicated in the maintenance of cell integrity, adhesion, and motility during tissue...
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Flapwing Dephosphorylates Merlin and Moesin and Regulates Epithelial Integrity in Drosophila
DownloadFall 2013
Merlin is a tumor suppressor protein whose inactivation is associated with familial Neurofibromatosis Type II (NF2) and other sporadic tumors. The growth-suppressive function of Merlin is modulated by reversible phosphorylation. Our previous finding showed the Sterile20 kinase Slik coordinately...
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Fall 2014
Taking cues from the work of Paul W. Schroeder, this project seeks to investigate the particular conditions which allowed the Habsburg Monarchy and two of its leading politicians—Leopold II and Metternich—to have such pride of place in Schroeder’s ‘transformation’ of the European state-system. It...
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Fall 2014
This thesis delineates a qualitative research approach that investigates immigrant students’ learning and social experiences in Greek state schools. The purpose of this research was to gain deeper insights into the life and learning experiences of immigrant students and to explore the ways in...
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2017-08-22
Molnar, Amber O., Barua, Moumita, Konvalinka, Ana, Schick-Makaroff, Kara
Purpose of Review: Patient engagement in research is increasingly recognized as an important component of the research process and may facilitate translation of research findings. To heighten awareness on this important topic, this review presents opportunities and challenges of patient...
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2020-08-01
This is a transcription of Paul Mascarene’s eighteenth-century translation of Molière’s Le Misanthrope, based on an undated and untitled manuscript that is bound in a volume with other records from Mascarene’s time as a military and civic leader in British Nova Scotia, held in the British...
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Fall 2011
Mutations in the NF2 gene lead to the disease Neurofibromatosis Type II which is characterized by the formation of multiple tumours in the central nervous system. The NF2 gene encodes the protein Merlin. Merlin interacts with a number of different proteins and these interactions may be important...