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Skip to Search Results- 1Adame Perez, Stephany
- 1Asaad, Ghada A
- 1Fontaine, Melanie A
- 1Hashemi, Seyede Zohre
- 1Ju, Tingting
- 1Li, Jiaying
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Antimicrobial activity of flavan-3-ols and oligomeric proanthocyanidins from pea seed coats and grape seeds against food and gut bacteria
DownloadFall 2017
Proanthocyanidins and their monomeric subunits flavan-3-ols belong to the polyphenol group of flavonoids. They have been proposed to exert health promoting effects against cancer, Type 2 diabetes and coronary disease among other conditions. These health promoting effects are believed to be...
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Assessment of food accessibility, availability and adherence to dietary recommendations among diabetic older adults living in subsidized retirement homes
DownloadSpring 2012
The availability and accessibility of healthy foods for type 2 diabetes patients may limit their food choices and adherence to dietary recommendations. The accessibility and availability of food for low-income, diabetic, older adults was evaluated. Information was gathered regarding self-care...
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Blood Glucose-attenuating Effects of Pea-derived Fractions: Exploration of Mechanisms of Action in a Rat Model of Glucose Intolerance
DownloadFall 2015
Pulses, including dried peas, are nutrient-dense foods rich in fibre that have shown efficacy in improving glucose control in diabetic subjects. The seed coats, in spite of being the highly fibrous part, are sometimes discarded as a food-processing by-product. We hypothesized that supplementing...
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Fall 2019
Changes in the gut microbiota have been correlated with positive and negative health outcomes; however, the mechanisms of causality in microbial modifications and resulting host responses are largely unknown. In this thesis, a mouse model was successfully established by colonizing mice with gut...
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Feeding high oleic acid Canola oil or olive oil alters inflammation, insulin resistance and lipid metabolism in a rodent model of diet induced obesity
DownloadFall 2011
To determine the efficacy of feeding monounsaturated fatty acids (MUFA) via a high MUFA Canola oil on T2D risk factors diet induced obese rats were fed either a low fat diet (LF), a high fat low MUFA diet (HF), a high fat high MUFA olive oil diet (OO), or a high fat high MUFA Canola oil diet...
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Long-term effects of early-life gut microbiota perturbations on pancreatic islet development
DownloadFall 2021
Impaired secretion of insulin from pancreatic beta-cells, along with loss of cell mass, is one of the hallmarks of the pathogenesis of type 2 diabetes, a metabolic disorder characterized by chronic hyperglycemia. In humans, beta-cells’ ability to secrete insulin in response to glucose is acquired...
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Long-term Impacts of Early Life Antibiotic Exposure on Intestinal Microbiota and Metabolic Disease
DownloadFall 2015
Although genetic factors, diet choices and sedentary lifestyle have long been considered main risk contributors for obesity and diabetes mellitus, years of study show that these factors cannot fully explain the increasing rate of worldwide metabolic disease. Epidemiological studies in recent...
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Nutritional Factors Impacting Intestinal Lipid Metabolism Using a Model of Low Birth Weight Swine
DownloadSpring 2018
Introduction: Non-communicable diseases (NCDs) such as obesity, type 2 diabetes (T2D) and cardiovascular disease (CVD) are increasing at an alarming rate globally. A common feature in these conditions is increased adiposity leading to insulin resistance (IR). Dyslipidemia is a major contributing...
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Vitamin D Status and Health-care Outcomes in an Ambulatory Population of Patients with Diabetes and Chronic Kidney disease: A Five-year Follow-up.
DownloadSpring 2018
Vitamin D (VitD) deficiency is a prevalent condition in Canada, especially in northern latitudes where sunlight exposure is limited. Elderly patients especially those with chronic conditions such as Diabetes Mellitus (DM) and Chronic Kidney Disease (CKD) have a higher risk of developing vitD...
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Vitamin D Supplementation and Bone Health in Adults with Diabetic Nephropathy: Preliminary Findings from a Randomized Controlled Trial
DownloadFall 2013
Vitamin D (vitD) is a nutrient of concern in Canada particularly for those with diabetes and chronic kidney disease (CKD). Participants (18-80y) with diabetes and CKD were randomized to receive either 50mcg/day (n=33) or 1,000mcg/month (n=30) vitD3 for 6-months. Variables studied included:...