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COUP-TF1 antagonizes Nkx25-mediated activation of the calreticulin gene during cardiac development
Download2001-01-01
Guo, Lei, Lynch, Jeffrey, Nakamur, Kimitoshi, Fliegel, Larry, Kasahara, Hideko, Izumo, Seigo, Komuro, Issei, Agellon, Luis B., Michalak, Marek
Calreticulin, a Ca2+ binding chaperone of the endoplasmic reticulum, is also highly expressed in the embryonic heart, and knockout of the calreticulin gene is lethal during embryogenesis because of impaired cardiac development. The protein is down-regulated after birth, and elevated expression of...
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MicroRNA Buffering and Altered Variance of Gene Expression in Response to Salmonella Infection
Download2014
Plastow, G. S., Bao, H., Kommadath, A., Guan, L. L., Tuggle, C. K., Stothard, P.
One potential role of miRNAs is to buffer variation in gene expression, although conflicting results have been reported. To investigate the buffering role of miRNAs in response to Salmonella infection in pigs, we sequenced miRNA and mRNA in whole blood from 15 pig samples before and after...
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2000
In photosynthetic organisms it is becoming increasingly evident that light-driven shifts in redox potential act as a sensor that initiates alterations in gene expression at both the level of transcription and translation. This report provides evidence that the expression of a cyanobacterial RNA...
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Regulation of cold shock-induced RNA helicase gene expression in the cyanobacterium Anabaena sptrain PCC 7120
Download2000
Owttrim, George W., Chamot, Danuta
Expression of the Anabaena sp. strain PCC 7120 RNA helicase gene crhC is induced by cold shock.crhC transcripts are not detectable at 30°C but accumulate at 20°C, and levels remain elevated for the duration of the cold stress. Light-derived metabolic capability, and not light per se, is required...
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Regulation of Na+/H+ Exchanger Gene Expression: Role of a poly T rich region in regulation of expression of the NHE1 promoter
Download1996-01-01
Yang, Weidong, Wang, Huayan, Fliegel, Larry
In this study we examine regulation of expression of the Na+/H+ exchanger promoter in L6 and NIH 3T3 cells. We have identified a highly conserved poly(dA·dT)-rich region that appears to be important in regulation of expression of the NHE1 gene. Deletion or mutation of this region results in...
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2004
A transcription of Russell's marginal comments in his copies of Frege's works, from his readings of Frege in 1902. The greatest number are in the early sections of Grundgesetze der Arithmetik, Vol. I, but there are also marginal comments in Begriffsschrift, Grundlagen der Arithmetik, \"Ueber...
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Separable whorl-specific expression and negative regulation by enhancer elements within the AGAMOUS second intron
Download2000
Deyholos, M. K., Sieburth, L. E.
We analyzed the 4-kb intragenic control region of the AGAMOUS (AG) gene to gain insight into the mechanisms controlling its expression during early flower development. We identified three major expression patterns conferred by 19 AG::reporter gene constructs: the normal AG pattern, a...