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- 2Mesenchymal stem cells
- 1Articular cartilage
- 1Biomaterial scaffold
- 1Bone marrow-derived mesenchymal stem cell
Development of the axial skeleton in vertebrates begins with the segmentation of the paraxial mesoderm into somites. Somites are transient structures in the embryos that ultimately give rise to the skeletal muscle, dermis, tendons, cartilage, and bony structures of the axial skeleton. Once...
The intricate arrangement and composition of articular cartilage confer the structure its unique material and mechanical properties. Degeneration of articular cartilage, especially osteoarthritis, imposes great burden not only on the patients, but also on society. While there exist various...
Articular cartilage injury is a major risk factor for the development of osteoarthritis, a condition that results in significant patient morbidity and substantial cost to the healthcare system. Due to the limited capacity of articular cartilage to regenerate, early intervention is required to...