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Skip to Search Results- 2Young, T. Kue
- 1Adams, Scott C
- 1Al-musawi, Maryam
- 1Alberta Centre for Active Living
- 1Anderson, T.
- 1Archer, S.
- 16Graduate and Postdoctoral Studies (GPS), Faculty of
- 16Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 2Agricultural, Food and Nutritional Science, Department of
- 2Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
- 2Biological Sciences, Department of
- 2Biological Sciences, Department of/Journal Articles (Biological Sciences)
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Cardiovascular Disease Risk factors in Canadian-born and Immigrant Children and Youth in the Canadian Health Measures Survey
DownloadFall 2014
Immigrants make up almost 20% of Canada’s population. Recent adult immigrants to Canada are generally in better health than those born in Canada. However, we know little about whether this is also the case in children. We compared mean levels and prevalence of adverse levels of CVD risk factors...
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Fall 2013
Rural residents face numerous barriers to health care access that have been postulated to result in decreased utilization and adherence to evidence-based medications. The objectives of this research were to examine cardiovascular medication use and adherence for rural versus urban patients with...
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Characterization of a novel model of intestinal lipoprotein overproduction and the impact of N-3 PUFA supplementation
DownloadFall 2009
Overproduction of intestinal chylomicrons (CM) has been proposed to contribute to fasting and post-prandial (PP) dyslipidemia and may accelerate the development of cardiovascular disease (CVD) during obesity, insulin resistance (IR) and diabetes. However, the impact of morphological changes in...
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Common Low-Density Lipoprotein Receptor p.G116S Variant Has a Large Effect on Plasma Low-Density Lipoprotein Cholesterol in Circumpolar Inuit Populations
Download2014-11-20
Dubé, Joseph B., Wang, Jian, Cao, Henian, McIntyre, Adam D., Johansen, Christopher T., Hopkins, Scarlett E., Stringer, Randa, Hosseinzadeh, Siyavash, Kennedy, Brooke A., Ban, Matthew R., Young, T. Kue, Connelly, Philip W., Dewailly, Eric, Bjerregaard, Peter, Boyer, Bert B., Hegele, Robert A.
"Background: Inuit are considered to be vulnerable to cardiovascular disease because their lifestyles are becoming more Westernized. During sequence analysis of Inuit individuals at extremes of lipid traits, we identified 2 nonsynonymous variants in low-density lipoprotein receptor (LDLR), namely...
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Contributions to chronic disease prevention and control: studies among the Kivalliq Inuit since 1990
Download2003-12-01
"A population-based health interview and examination survey of 8 Inuit communities in the Kivalliq region of Nunavut, Canada, during the early 1990s has resulted in an increased understanding of the burden and extent of cardiovascular diseases and diabetes and their risk factors such as genetics,...
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Spring 2014
Lower-extremity peripheral artery disease (PAD) is a manifestation of atherosclerotic disease in the lower limbs. PAD is a risk factor for poor outcomes including myocardial infarction, stroke, and mortality. Despite the potential benefits of early PAD detection, in the majority of PAD cases...
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Spring 2019
Phosphatidylcholine (PC), the most abundant phospholipid in eukaryotic cells, is an important component of cellular membranes and lipoprotein particles. The enzyme CTP: phosphocholine cytidylyltransferase (CT) regulates de novo PC synthesis in response to changes in membrane lipid composition in...
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Delineation of molecular mechanisms of intestinal calcium absorption during postnatal development
DownloadFall 2021
Infants and children must maintain a positive calcium balance for appropriate growth. Evidence suggests that adaptations in intestinal absorption of calcium are the major determinant of this net balance. However, the molecular details of the pathways mediating this increased absorption at a young...
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Spring 2014
Major depression (MD) is one of the most prominent medical conditions worldwide in terms of societal cost and morbidity. MD has been associated with increased risk for cardiovascular disease (CVD) and conversely CVD has been associated with increased MD symptoms. Previous studies have shown that...
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Dietary lipids containing gangliosides reduce Giardia muris infection in vivo and survival of Giardia lamblia trophozoites in vitro
Download2004
Suh, M., Belosevic, M., Clandinin, M.T.
We examined whether a ganglioside supplemented diet affected the course of Giardia muris infection in mice and survival of Giardia lamblia trophozoites in vitro. Female CD-1 mice were fed 1 of 5 experimental diets : standard lab chow as a control diet; semi-synthetic diets containing 20% (w/w)...