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Cardiovascular Disease Risk factors in Canadian-born and Immigrant Children and Youth in the Canadian Health Measures SurveyDownload
Immigrants make up almost 20% of Canada’s population. Recent adult immigrants to Canada are generally in better health than those born in Canada. However, we know little about whether this is also the case in children. We compared mean levels and prevalence of adverse levels of CVD risk factors...
Rural residents face numerous barriers to health care access that have been postulated to result in decreased utilization and adherence to evidence-based medications. The objectives of this research were to examine cardiovascular medication use and adherence for rural versus urban patients with...
Characterization of a novel model of intestinal lipoprotein overproduction and the impact of N-3 PUFA supplementationDownload
Overproduction of intestinal chylomicrons (CM) has been proposed to contribute to fasting and post-prandial (PP) dyslipidemia and may accelerate the development of cardiovascular disease (CVD) during obesity, insulin resistance (IR) and diabetes. However, the impact of morphological changes in...
Lower-extremity peripheral artery disease (PAD) is a manifestation of atherosclerotic disease in the lower limbs. PAD is a risk factor for poor outcomes including myocardial infarction, stroke, and mortality. Despite the potential benefits of early PAD detection, in the majority of PAD cases...
Major depression (MD) is one of the most prominent medical conditions worldwide in terms of societal cost and morbidity. MD has been associated with increased risk for cardiovascular disease (CVD) and conversely CVD has been associated with increased MD symptoms. Previous studies have shown that...
Abstract: Objective To synthesise the literature on the effects of fish oil - docosahexaenoic acid ( DHA) and eicosapentaenoic acid ( EPA) - on mortality and arrhythmias and to explore dose response and formulation effects. Design Systematic review and meta- analysis. Data sources Medline,...
Effects of High-Intensity Aerobic Interval Training on Cardiovascular Disease Risk and Health-related Quality of Life in Testicular Cancer Survivors: The HIITTS TrialDownload
Background: Testicular cancer (TC) survivors (TCS) are an understudied, high-risk group susceptible to late-onset treatment-related cardiovascular disease (CVD), psychosocial, and health-related quality of life (HRQoL) deficits in the years following treatment. Importantly, despite having the...
McCarthy, G., Crichton, N.J., Linck, T., Seers, K., Titchen, A., Kitson, A., Edwards, R.T., Wallin, L., Hawkes, C., Estabrooks, C.A., Mockford, C., Cox, K., Harvey, G., Eldh, A.C., McCormack, B., Rycroft-Malone, G.
Background: Research evidence underpins best practice, but is not always used in healthcare. The Promoting Action on Research Implementation in Health Services (PARIHS) framework suggests that the nature of evidence, the context in which it is used, and whether those trying to use evidence are...
Innovative strategic Canadian research training from TomorrOw’s Research Cardiovascular Health Care Professionals (TORCH).Download
Cardiovascular research training is experiential, and \"skills\" are traditionally acquired through a master-apprentice paradigm. The complexity of contemporary clinical research requires a new model for research training. Facilitated through a Strategic Training Program Initiative, the Canadian...
Mental health and chronic medical conditions: schizophrenia, its treatment, risk of metabolic complications, and health care utilizationDownload
Objective - To assess the relationship between schizophrenia and cardiovascular disease by evaluating metabolic risk associated with treatment for schizophrenia, prevalence of cardiovascular risk factors (CV-RF) and disease (CV-D), and health care utilization in people with schizophrenia...