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- 9Clinical trials
- 6Randomized controlled trials
- 5Child health
- 5Influenza vaccinations
- 5Knowledge translation
- 22Nursing, Faculty of
- 22Graduate and Postdoctoral Studies (GPS), Faculty of
- 22Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 19Medicine and Dentistry, Faculty of
- 14Nursing, Faculty of/Health Systems
- 14Medicine and Dentistry, Faculty of/Alberta Research Centre for Health Evidence (ARCHE)
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The impact of bias on the magnitude of treatment effect estimates in oral health randomized trials
DownloadFall 2016
Background: There is emerging evidence that randomized trials are subject to biases. Flaws in the design of such trials can result in over- or underestimation of the treatment effect size. Aim: To examine the empirical evidence for bias, to quantify the extent of bias associated with methodology,...
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The pharmaceutical industry’s willingness-to-sell targeted chemotherapy for incurable solid cancers
DownloadSpring 2013
How the costs of research and its associated risks contribute to a minimum price that would support continued private pharmaceutical investment is unclear. We employed a linear cost-volume-revenue breakeven analysis to equate initial capital investment and risk, and its associated...
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The validity, reliability and time requirement of study model analysis using cone-beam computed tomography generated virtual study models
DownloadFall 2011
Objectives: To investigate the validity, reliability and time spent on performing a full orthodontic study model analysis (SMA) on Cone Beam Computed Tomography (CBCT)-generated dental models (Anatomodels) compared with conventional Plaster models and a subset of Extracted Premolars. Methods:...
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Spring 2010
The increasing popularity of traditional Chinese medicine (TCM) therapies as health care options warrants thorough examination of the efficacy and safety evidence around these therapies. This thesis explores the intersection of TCM and fatigue using two rigorous methodologies: systematic reviews...
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Fall 2012
Individuals with type 2 diabetes (T2DM) have an increased risk of bladder cancer, relative to non-diabetic individuals. We aimed to investigate factors that may influence this association. Some reports suggest an association between the glucose-lowering drug pioglitazone and bladder cancer. Our...
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Which resources should be used to identify RCT/CCTs for systematic reviews: a systematic review.
Download2005
Cramer, K., Hartling, L., Wiebe, N., Klassen, T. P., Crumley, E. T.
Background Systematic reviewers seek to comprehensively search for relevant studies and summarize these to present the most valid estimate of intervention effectiveness. The more resources searched, the higher the yield, and thus time and costs required to conduct a systematic review. While there...
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Fall 2014
Work engagement in nursing practice is critically important to consider in addressing key challenges of health systems, including the global nursing shortage, pressures to reduce health care spending, and increasing demands for quality care and positive outcomes for patients. There is a...