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- 3Löbenberg, Raimar
- 2Azarmi, Shirzad
- 2Finlay, Warren H.
- 2Roa, Wilson
- 1Dennis, Jonathan J.
- 1Dickau, Matthew A
- 6Graduate Studies and Research, Faculty of
- 6Graduate Studies and Research, Faculty of/Theses and Dissertations
- 3Pharmacy and Pharmaceutical Sciences, Faculty of
- 3Pharmacy and Pharmaceutical Sciences, Faculty of/Journal Articles (Pharmacy)
- 1Biological Sciences, Department of
- 1Biological Sciences, Department of/Journal Articles (Biological Sciences)
Particulate matter emitted from two direct injection engines has been characterized by morphology, volatility, mass-mobility exponent, effective density, and size distribution using tandem measurements from a centrifugal particle mass analyzer (CPMA) and differential mobility analyzers (DMA). The...
Development of Empirical Models to Predict Deposition of Aerosols in the Extrathoracic Airways of ChildrenDownload
The experimental studies described in this thesis were performed with the goal of measuring deposition of aerosols, inhaled either nasally or orally, in the extrathoracic airways of children in different age groups. We pursued in vitro methods and characterized the deposition of aerosols in the...
Improving Measurements of the Mixing State and Mass Concentration of Particulate Emissions from Aircraft EnginesDownload
This research is focused towards improving techniques used to measure particulate emissions from aircraft engines, on two fronts: first, to characterize and quantify the mixing state of particulate emissions; and second, to calibrate black carbon mass instruments with a traceable mass...
The centrifugal particle mass analyzer (CPMA)-electrometer system has been proposed as an alternative method of calibration for devices that measure black carbon. This system is proposed to replace the current calibration standard of NIOSH 5040. The repeatability and intermediate precision of the...
Study of Enhanced Deposition due to Magnetic Field Alignment of Ellipsoid Particles Using Direct Numerical SimulationsDownload
A recent in vitro study demonstrated a non invasive method to enhance local deposition in a small airway by controlling the angular position of magnetic high aspect ratio particles. This technique could mitigate the challenge of providing sufficient therapeutic effects when using aerosolized...
Toward Modern Inhalational Bacteriophage Therapy: Nebulization of Bacteriophages of Burkholderia cepacia ComplexDownload
Antibiotic-resistant bacterial infections have renewed interest in finding substitute methods of treatment. The purpose of the present in vitro study was to investigate the possibility of respiratory delivery of a Burkholderia cepacia complex (BCC) bacteriophage by nebulized aerosol...
Most current models for the deposition of aerosol particles in the human lung are based on a Lagrangian reference frame, which is ill-suited for modeling transient eects. Deposition models based on an Eulerian reference frame are much better at capturing instantaneous time-dependent eects, though...