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Skip to Search Results- 78Graduate and Postdoctoral Studies (GPS), Faculty of
- 78Graduate and Postdoctoral Studies (GPS), Faculty of/Theses and Dissertations
- 35Rehabilitation Medicine, Faculty of
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- 78Thesis
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Adiposity and fat loss in cancer: Exploring the prognostic significance and underlying mechanisms of adipose alterations in cancer
DownloadSpring 2017
During cancer progression, many patients will experience some degree of wasting of both muscle and adipose tissue. However, little is-known about adipose tissue alterations after a cancer diagnosis. Therefore, this research was conducted to first understand the prognostic significance of adipose...
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Spring 2023
Wheelchair-mounted robotic manipulators have the potential to help the elderly and individuals living with disabilities carry out their activities of daily living independently. While robotics researchers focus on assistive tasks from the perspective of various control schemes and motion types, ...
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Anti-Cancer Mechanism of Trastuzumab via Blocking Nuclear HER2 Function and Epigenetic Mechanism of Resistance
DownloadSpring 2020
HER2 receptor tyrosine kinase (encoded by ERBB2 gene) is overexpressed in approximately 25% of all breast cancer tumors (known as HER2-positive breast cancers). Overexpression of HER2 causes overactivation of downstream receptor tyrosine kinase pathways including PI3K/Akt and MAPK pathways and is...
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Fall 2009
There is substantial evidence of the elevated risk of cancer among individuals with type 2 diabetes. Very little is known, however, about the role that antidiabetic therapies play in this relationship. The objective of this program of research was to examine whether there is a therapeutic risk...
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Application of ROC curve analysis to metabolomics data sets for the detection of cancer in a mouse model
DownloadFall 2010
The goal of this study was to show that quantifiable metabolic changes may be used to screen for cancer. NIH III nude mice (n=22) were injected with human GBM cells, with daily urine samples collected pre and post-injection. 14 mice were injected with saline to serve as controls. The...
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Back2Future-SIM: Creating Real-Time Interactable Immersive Virtual World For Robot Teleoperation
DownloadSpring 2024
In the context of human-robot interaction (HRI), robot autonomy addresses how environmental input influences a robot’s actions, spanning a spectrum from full human control to independent robot motion. The quality of HRI relies on information exchange, evaluated through factors like interaction...
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Fall 2018
Background: Cancer-associated venous thromboembolism (VTE) is associated with significant morbidity and mortality. Cancer patients are at higher risk of VTE recurrence despite anticoagulation and bleeding complications while on anticoagulation. There are some risk factors of bleeding specific...