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Skip to Search Results- 1Abdulsalam Alharbi
- 1Aktary, Zackie M
- 1Alolayan, Waad Riyad
- 1Alshamsan, Aws
- 1Alvarado, Laura
- 1Amritpal Singh Bhullar
- 12Faculty of Rehabilitation Medicine
- 8Department of Oncology
- 6Faculty of Pharmacy and Pharmaceutical Sciences
- 5Centre for Neuroscience
- 5Department of Agricultural, Food, and Nutritional Science
- 3Department of Chemical and Materials Engineering
- 3Lavasanifar, Afsaneh (Faculty of Pharmacy and Pharmaceutical Sciences)
- 3McNeely, Margaret (Rehabilitation Medicine)
- 2Haennel, Bob (Faculty of Rehabilitation Medicine)
- 2Hebert, Jacqueline (Medicine)
- 2Uludag, Hasan (Chemical and Materials Engineering)
- 1Aalto, Daniel (Rehabilitation Medicine)
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Fall 2018
The adoption of powered myoelectric prostheses and their ability to improve quality of life for persons with amputations is hindered by the difficulty of controlling multiple degrees of freedom with a limited number of input signals. Different myoelectric control strategies have been developed to...
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Development of Novel Polymeric Micellar DACHPt for Enhanced Platinum Based Chemotherapy in Colorectal Cancer
DownloadSpring 2019
One of the major limitations of chemotherapy in cancer treatment is the side effects of anti-cancer drugs. This happens due to non-selective distribution of most standard chemotherapies, and their action on cancer and all normal dividing cells. The objective of this project is to develop a novel...
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Fall 2013
The aim of this work is to develop an effective non-viral carrier and to identify suitable gene targets that would induce apoptosis specifically in lymphoma cells upon down-regulation with short interfering RNA (siRNA). Lymphoma is common in children and young adults, and although survival rate...
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Development of block copolymer based nanocarriers for the solubilization and delivery of valspodar
DownloadFall 2011
One of the major causes of failure in cancer chemotherapy is multidrug resistance (MDR), where cancer cells become resistant to different types of anticancer drugs. Over-expression of membrane efflux pumps like P-glycoprotein (P-gp), which recognizes different chemotherapeutic agents and...
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Fall 2010
In many tumors, persistently-active signal transducer and activator of transcription 3 (STAT3) imparts several oncogenic features such as survival, proliferation, angiogenesis, and immune escape. Therefore, STAT3 targeting in cancer and cancer-exposed dendritic cells (DCs) is important for cancer...
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EASE-BE-FIT: Elder-Friendly Approaches to the Surgical Environment Bedside Reconditioning for Functional Improvements An Innovative Reconditioning Program for Elderly Emergency Abdominal Surgery Patients
DownloadSpring 2017
Introduction: Elderly individuals who are hospitalized due to emergency abdominal surgery spend on average over 80% of their recovery time in bed, resulting in early and rapid muscle loss. As these elderly individuals have a lower physiological reserve, the impact of muscle wasting on function...
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Evaluation of Hypoxia Induced Regulation of Nucleoside and Amino Acid Membrane Transporters in Breast Cancer
DownloadSpring 2020
Positron Emission Tomography (PET) utilizes radioactively tagged molecules to identify cancerous tissue. In most cases, membrane transporters control entry of these molecules into human cancer cells. Hypoxia-inducible factor (HIF)-1 is the master homeostatic regulator during hypoxia in human...
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Spring 2019
Energy expenditure forms the basis of all dietary recommendations. In patients with cancer, resting energy expenditure (REE) can be impacted by tumor burden, high systemic inflammation, and/or altered body composition. Total energy expenditure (TEE) and physical activity levels (PAL) have been...
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Fall 2020
Background: A standard treatment option for locally advanced rectal cancer includes 5-6 weeks of neoadjuvant chemoradiation (NACRT) followed by surgery about 6-8 weeks later. NACRT improves outcomes for rectal cancer patients but also causes acute toxicities which may impede quality of life...