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Skip to Search Results- 58Young, T. Kue
- 10Bjerregaard, Peter
- 10Chatwood, Susan
- 10Hegele, Robert A.
- 7Connelly, Philip W.
- 6Ban, Matthew R.
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Cardiovascular Risk According to Plasma Apolipoprotein and Lipid Profiles in a Canadian First Nation
Download2011
Riediger, Natalie D., Bruce, Sharon G., Young, T. Kue
"Introduction: Despite high diabetes rates among Canadian First Nations people, little is known about their cardiovascular disease risk. Our aim was to describe the apolipoprotein profile with respect to cardiovascular risk in a Canadian First Nation community. Methods: In 2003, a representative...
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Carotid Atherosclerosis and a Reduced Likelihood for Lowered Cognitive Performance in a Canadian First Nations Population
Download2009-10-30
Fergenbaum, Jennifer H., Bruce, Sharon, Spence, J.D., Lou, Wendy, Hanley, Anthony J.G., Greenwood, Carol, Young, T. Kue
"Background: We investigated the associations among cardiovascular risk factors, carotid atherosclerosis and cognitive function in a Canadian First Nations population. Methods: Individuals aged ≥18 years, without stroke, nonpreg- nant and with First Nations status were assessed by the Trail...
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Characteristics and prevalence of the metabolic syndrome among three ethnic groups in Canada
Download2005-11-22
Liu, Juan, Hanley, Anthony J. G., Young, T. Kue, Harris, S. B., Zinman, Bernard
"Objective: To compare the characteristics and prevalence of the metabolic syndrome (MetS) among Native Indians, Inuit, andnon-Aboriginal Canadians. Methods: The study was based on four cross-sectional studies conducted in the late 1980s and early 1990s involving threeethnic groups living in...
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Chronic Diseases and Risk Factors in Canada’s Northern Populations: Longitudinal and Geographic Comparisons
Download2009-01-01
Deering, Kahtleen N., Lix, Lisa M., Bruce, Sharon, Young, T. Kue
"Objective: Chronic diseases are the leading cause of death and disability worldwide and place considerable burden on the Canadian health care system. This research investigates the self-reported prevalence of major chronic diseases and risk factors in northern Canadian populations and compares...
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2013-08-05
Plenary session, 15th International Congress of Circumpolar Health. Topics: "(a) Who are circumpolar peoples? (b) How has our population changed? (c) Do we enjoy the same health? (d) Why are we unequal? (e) What are our health care challenges? and (f) What can the circumpolar health ‘‘community’’...
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2000-08-01
Wang, Jian, Burnett, John R., Near, Susan, Young, T. Kue, Zinman, Bernard, Hanley, Anthony J. G., Connelly, Philip W., Harris, Stewart B., Hegele, Robert A.
"Mutations in ABCA1, a member of the ATP-binding cassette family, have been shown to underlie Tangier disease (TD) and familial hypoalphalipoproteinemia (FHA), which are genetic disorders that are characterized by depressed concentrations of plasma high density lipoprotein (HDL) cholesterol. An...
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2001-06-01
Hegele, Robert A., Huff, Murray W., Young, T. Kue
"We discovered that rare mutations in LMNA, which encodes lamins A and C, underlie autosomal dominant Dunnigan-type familial partial lipodystrophy. Because familial partial lipodystrophy is an extreme example of genetically disturbed adipocyte differentiation, it is possible that common variation...
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Common Low-Density Lipoprotein Receptor p.G116S Variant Has a Large Effect on Plasma Low-Density Lipoprotein Cholesterol in Circumpolar Inuit Populations
Download2014-11-20
Dubé, Joseph B., Wang, Jian, Cao, Henian, McIntyre, Adam D., Johansen, Christopher T., Hopkins, Scarlett E., Stringer, Randa, Hosseinzadeh, Siyavash, Kennedy, Brooke A., Ban, Matthew R., Young, T. Kue, Connelly, Philip W., Dewailly, Eric, Bjerregaard, Peter, Boyer, Bert B., Hegele, Robert A.
"Background: Inuit are considered to be vulnerable to cardiovascular disease because their lifestyles are becoming more Westernized. During sequence analysis of Inuit individuals at extremes of lipid traits, we identified 2 nonsynonymous variants in low-density lipoprotein receptor (LDLR), namely...
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Common variants APOC3, APOA5, APOE and PON1 are associated with variation in plasma lipoprotein traits in Greenlanders
Download2007-12-01
Lahiry, Piya, Ban, Matthew R., Pollex, Rebecca L., Sawyez, Cynthia G., Huff, Murray W., Young, T. Kue, Bjerregaard, Peter, Hegele, Robert A.
"Objectives: We undertook studies of the association between common genomic variations in APOC3, APOA5, APOE and PON1 genes and variation in biochemical phenotypes in a sample of Greenlanders. Study Design: Genetic association study of quantitative lipoprotein traits. Methods: In a sample of...
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2018-07-08
Young, T. Kue, Fedkina, Natalia, Chatwood, Susan, Bjerregaard, Peter
"The eight Arctic States exhibit substantial health disparities between their remote northernmost regions and the rest of the country. This study reports on the trends and patterns in the supply and distribution of physicians, dentists and nurses in these 8 countries and 25 regions and addresses...