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A tale of two hypotheses: Effect of the herpes simplex-1 virus virion host shutoff (vhs) protein on bicistronic reporters
DownloadFall 2014
The herpes simplex virus virion host shutoff (vhs) protein acts as an mRNA specific endoribonuclease. Our lab has previously determined that vhs stimulates expression of the 3’ CAT cistron of a bicistronic reporter plasmid while under the influence of the BiP IRES; however, the mechanism by which...
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