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Skip to Search Results- 40Field, Catherine J.
- 21Proctor, Spencer D.
- 8Vine, Donna F.
- 6Goruk, Susan
- 6Mangat, Rabban
- 6Ruth, Megan R.
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Infant gut microbiota and the hygiene hypothesis of allergic disease: Impact of household pets and siblings on microbiota composition and diversity
Download2013
Field, Catherine J., Guttman, David S., Kozyrskyj, Anita L., Maughan, Heather, Sears, Malcolm R., Konya, Theodore, Scott, James A., Becker, Allan B., Azad, Meghan B.
Background Multiple studies have demonstrated that early-life exposure to pets or siblings affords protection against allergic disease; these associations are commonly attributed to the “hygiene hypothesis”. Recently, low diversity of the infant gut microbiota has also been linked to allergic...
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Insulin and testosterone are associated with elevated intestinal secretion of lipids and lipoproteins in a rodent model of the metabolic and polycystic ovary syndrome
Download2014
Wang, Ye, Shi, Danni, Proctor, Spencer D., Vine, Donna F.
The metabolic syndrome is highly associated with the incidence of Polycystic Ovary Syndrome (PCOS). The metabolic aberrations of insulin resistance and hyperandrogenemia have been proposed to contribute to the development of dyslipidemia and increased Cardiovascular Disease (CVD) risk in PCOS....
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2012
Ketabi, Ali, Baracos, Vickie E., Field, Catherine J., Lin, Xiaoxi, Xue, Hongyu, Bibova, Ilona, Gänzle, Michael G., Dieleman, Levinus A., Sawyer, Michael B.
Intestinal microbiota mediate toxicity of irinotecan (CPT-11) cancer therapies and cause systemic infection after CPT-11-induced loss of barrier function. The intestinal microbiota and their functions are thus potential targets for treatment to mitigate CPT-11 toxicity. However, microbiota...
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2016-01-01
Singh, V. P., Proctor, Spencer D., Willing, Ben P.
Over the past 20 years, a growing amount of evidence supports the role of microbes and an imbalanced microbiota in inflammatory bowel disease (IBD). While many reviews have been written on the microbiota in IBD, few have considered how they fulfil the Koch's postulates. In this review, we...
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Long-term catheterization of the intestinal lymph trunk and collection of lymph in neonatal pigs
Download2016-01-01
Uwiera, Richard R., Mangat, Rabban., Kelly, Sandra, Uwiera, Trina C., Proctor, Spencer D.
Catheterization of the intestinal lymph trunk in neonatal pigs is a technique allowing for the long-term collection of large quantities of intestinal (central) efferent lymph. Importantly, the collection of central lymph from the intestine enables researchers to study both the mechanisms and...
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Long-term effect of docosahexaenoic acid feeding on lipid composition and brain fatty acid-binding protein expression in rats
Download2015
Moncton, Elizabeth A., Brun, Miranda, Emara, Marwan, Field, Catherine J., Goruk, Susan, Godbout, Roseline, Elsherbiny, Marwa E., Richard, Caroline
Arachidonic (AA) and docosahexaenoic acid (DHA) brain accretion is essential for brain development. The impact of DHA-rich maternal diets on offspring brain fatty acid composition has previously been studied up to the weanling stage; however, there has been no follow-up at later stages. Here, we...
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2014
Bridgman, Sarah L., Letourneau, Nicole, Field, Catherine J., Azad, Meghan B., Johnston, David W., Kozyrskyj, Anita L., Kaplan, Bonnie J.
Background Probiotic products that may modify the intestinal microbiota are becoming increasingly available and known to consumers due to their potential to prevent or treat many pediatric health conditions. As scientific knowledge of the health benefits of probiotics increases, it is important...
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n-3 fatty acids inhibit transcription of human IL-13: Implications for development of T helper type 2 immune responses
Download2013
Cameron, Lisa, Madsen, Norman, MacLean, Emily, Vliagoftis, Harissios, Field, Catherine J.
Fish oil supplementation during pregnancy has been associated with lower levels of cord blood IL-13, suggesting that the administration of n-3 fatty acids may attenuate the development of allergic disease. The present study aimed to investigate the mechanism by which n-3 fatty acid administration...
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2011-01-01
Xue, Hongyu, Field, Catherine J.
New role of glutamate as an immunoregulator via glutamate receptors and transporters.
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Prenatal micronutrient supplementation and postpartum depressive symptoms in a pregnancy cohort
Download2013
Tough, Suzanne, Gomez, Mariel F., Eliasziw, Misha, Gagnon, Lisa, Field, Catherine J., Kaplan, Bonnie J., Leung, Brenda M., McCargar, Linda
Background Postpartum depression is a serious problem for women and their offspring. Micronutrient supplements are recommended for pregnant women because of their documented protective effects for the offspring, but their potential beneficial effects on maternal mental health are unknown. This...