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Spring 2021
The exposure of DNA to UV radiation can lead to deletions, strand breaks or base modifications such as the formation of cyclobutane pyrimidine dimers (CPDs), [6-4] pyrimidine-pyrimidinones, and photohydrates, which may then lead to skin cancer. Different methods have been developed for the...
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V-CoHOG: Volumetric Co-occurrence Histograms of Oriented Gradients for Texture Classification in Medical Imaging
DownloadFall 2022
Image textures, which are properties that can describe the pixel intensities of an image, have been analyzed in order to perform a variety of tasks, including segmentation and classification. Features derived from textures which are invariant to changes such as contrast and transformations are of...
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Spring 2017
In the Japanese language, it is known that when the evidential -soo da ‘looks like’ connects to a negative predicate, an additional element sa occasionally appears between the negative marker and -soo da, giving rise to two different forms, -na-soo da and -nasa-soo da. An example is shown below: ...
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Fall 2014
Two types of robust designs, robust design against a misspecified response function and robust design against autocorrelation, are reviewed in the first chapter of this dissertation. Among robust designs against autocorrelation, this dissertation focuses on V-robust designs. Chapter 2 reviews and...
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Vaccinations of Children from Im/migrant Families in Alberta: Equity-Oriented Critical Policy Analysis
DownloadSpring 2022
Immigrant and refugee (im/migrant) families settled in Alberta (AB) are often challenged to overcome structural barriers (i.e., accent discrimination, English as a foreign language, culture shock) in the way of navigating and actively utilizing vaccination services. Research is scarce on the...
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Vaccinia virus DNA polymerase and ribonucleotide reductase: their role in replication, recombination and drug resistance
DownloadSpring 2010
Despite the eradication of smallpox, poxviruses continue to cause human disease around the world. At the core of poxvirus replication is the efficient and accurate synthesis and repair of the viral genome. The viral DNA polymerase is critical for these processes. Acyclic nucleoside phosphonate...
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Fall 2021
Poxviruses encode many genes that are orthologs of cellular genes. These orthologs serve many functions, but those that are of most interest are ones that have evolved further and now serve an immune-evasion function. Such genes were likely first acquired by poxviruses through some form of...
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Spring 2012
Abstract In this dissertation, I examine the combinatorial properties of valence-increasing suffixes (i.e., the causative and applicatives), and the semantic and syntactic effects of combining these suffixes with a verb stem in the Yoni dialect of Temne, a Southern Atlantic language of the...