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Skip to Search Results- 3Mass-spectrometry
- 3Metabolomics
- 2Metabolome analysis
- 1Butanol
- 1Chemical isotope labeling
- 1Isotope labeling
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Comparative proteomic and metabolomic analysis of a Staphylococcus variant (SG1) cultured in the presence and absence of butanol
DownloadFall 2013
My research focuses on proteomic and metabolomic analysis of a solvent tolerant strain of Staphylococcus warneri called SG1 cultured in the presence and absence of 1-Butanol. On the proteomic analysis, the tryptic digests of SG1 were either directly analyzed by two-dimensional liquid...
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Development and Application of Chemical Isotope Labeling Methods and Metabolite Identification Solution for Liquid Chromatography-Mass Spectrometry-Based Metabolomics
DownloadFall 2018
Metabolomics, the comprehensive analysis of small molecules in biological specimens, has become an emerging and indispensable tool for systems biology and clinical research. Liquid chromatography-mass spectrometry (LC-MS) is a dominant analytical platform for metabolomics, featuring high...
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Development and application of mass spectrometry for bioanalysis of proteins and metabolites
DownloadSpring 2011
The proteome, a hybrid term from protein and genome, is the total set of proteins expressed by a genome in a cell, tissue, or organism at a given time. Proteomics, the study of the proteome, is concerned with a variety of topics such as identity, quantity, activity, structure, protein-protein...
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Development of isotope labeling liquid chromatography mass spectrometry for metabolome analysis
DownloadSpring 2011
As the endpoint of the “omics” cascade, metabolomics has attracted much attention in the discovery of diagnostic or prognostic disease biomarkers, and as a powerful tool to understand biological and biochemical processes and mechanisms. The objective of my research was to develop a highly...
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Development of Isotope Labeling Methods and Data Processing Program for Liquid Chromatography Mass Spectrometry-Based Metabolome Analysis
DownloadSpring 2014
Metabolomics strives to gain a comprehensive picture of the metabolites in a biological system. This emerging research field gives us an insight into the discovery of disease-related biomarkers and an understanding of metabolic flux as well as mechanisms. Liquid chromatography mass spectrometry...
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Spring 2022
Metabolomics, as an interdisciplinary research area, requires the integration of knowledge from different disciplines, such as analytical chemistry, bioinformatics, and statistics. The general workflow of metabolome analysis includes sample preparation, data acquisition, data processing, data...