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Fall 2015
Congenital hereditary endothelial corneal dystrophy type 2 (CHED2), Harboyan Syndrome (HS) and Fuchs endothelial corneal dystrophy (FECD) are caused by SLC4A11 mutations. The majority of SLC4A11 point mutations cause SLC4A11 misfolding and retention in the endoplasmic reticulum (ER). This impairs...
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Fall 2015
The validity and reliability of a test may be compromised because of the presence of misfitting response patterns in test data. Consequently, the purpose of the present study was to investigate the effects of the inclusion and exclusion of misfitting response patterns on item parameter estimates...
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Fall 2016
Steam-solvent coinjection has been studied and pilot-tested as a potential method to improve steam-assisted gravity drainage for bitumen recovery. Reliable design of coinjection requires reliable PVT data for bitumen/solvent/water mixtures, which are scarce and fragmentary in the literature. ...
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Comparative Analysis of the Anatomy of the Myxinoidea and the Ancestry of Early Vertebrate Lineages
DownloadFall 2012
The question of whether a hagfish is a true vertebrate or not has profound implications about the ancestry of the clade. New anatomical evidence allows a test of their systematic position. With dissections and serial sections of original specimens, and with a literature review, a comparative...
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Fully sequential monitoring of longitudinal trials using sequential ranks, with applications to an orthodontics study
DownloadFall 2009
This thesis explores the application of fully sequential methods for the analysis of longitudinal clinical trial data. A new nonparametric approach will be developed, using sequential ranks, for the comparison of several treatment groups. Sequential ranking is an alternative to ranking by the...
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Spring 2018
Skin cancer is one of the common and most fatal cancers. Therefore, it is important to be able to diagnose skin lesions and detect this cancer before it is too late. Learning to distinguish between sick and healthy lesions is key. However, there are two levels in which one can learn to...
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Integrated Hollow-Core Microcavity Arrays - Building Blocks for Optical Sensing and Quantum Information
DownloadFall 2017
This thesis describes an experimental and theoretical study of a novel class of air-core microcavities on chips, monolithically fabricated by the controlled formation of delamination buckles within a-Si/SiO2-based multilayer thin film stacks. First, arrays of dome-shaped microcavities were...