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Skip to Search Results- 1Abdul Rahman, Siti Aishah
- 1Acton, Leah T
- 1Aghamohammadi Sereshki, Arash
- 1Ainsley, Emily N.
- 1Bandet, Mischa V.
- 1Batty, Nicholas J.
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Investigating the Behavioral and Neural Impact of Skill and Goal-based Interventions in Adults with Dyslexia
DownloadSpring 2023
Developmental dyslexia is a neurodevelopmental disorder that is characterized by persistent reading and spelling difficulties despite adequate intelligence and educational opportunities. In addition to literacy-based difficulties, individuals with dyslexia also have difficulties with their...
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Fall 2019
Acquisition and storage of episodic-like information fundamentally contributes to quality of life. It is the type of information that allows us to remember meaningful events such as our graduation and our heartaches. The memory of these events allows us to adapt our behaviours to facilitate more...
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Fall 2020
Intracerebral hemorrhage (ICH), when a blood vessel ruptures within the brain, affects approximately 15% of stroke victims in Canada. There are no proven neuroprotective treatments ICH but two therapies, therapeutic hypothermia (TH) and iron-chelators, have gained preclinical and clinical...
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Fall 2021
Intraspinal microstimulation (ISMS) is a neural prosthetic technique which can restore locomotor function in models of severe spinal cord injury (SCI). Historically, ISMS has been implemented with microwire electrodes or rigid multielectrodes, which suffer from limitations related to either...
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Locomotion-related propriospinal V3 interneurons modulate sensory-transmission to motoneurons by generating primary afferent depolarization
DownloadFall 2022
Proprioceptive sensory-evoked reflexes are essential in assisting the precision of basic movements and maintenance of body postures. The motor outputs from these reflexes are precisely calibrated to avoid interfering with the ongoing motor functions. After spinal cord injury (SCI), reflexes...
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Spring 2019
Walking is a locomotor task that integrates information from all over the nervous system. The lumbosacral spinal cord houses neural networks that contribute to locomotion. These networks dominate locomotor activity during development and may provide suitable targets for restoring function after...
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Spring 2023
The overall goal of this work was to design an intelligent method to reduce the cognitive and physical burdens associated with walking using lower-limb exoskeletons after paralysis. Lower-limb exoskeletons with many operating modes (i.e., walking patterns) can be challenging to work with....
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Fall 2018
The peripheral nervous system (PNS) is often damaged by physical trauma or by diseases known as neuropathies. Currently, there are no effective treatments for augmenting repair of damaged nerves. Although the PNS is considered to be more plastic than the central nervous system, recovery outcomes...
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Fall 2021
Spinal cord injury (SCI) not only leads to motor and sensory dysfunction, but just as debilitating are secondary consequences of SCI such as bowel disorders, neuroinflammation, immune suppression, pain and psychiatric disorders. In this thesis, I explore multiple aspects of recovery after SCI in...
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Mechanisms underlying P2Y1 receptor-mediated excitation of the inspiratory network in vitro; and NPY-induced stress resilience in vitro and in vivo
DownloadSpring 2021
The present thesis will discuss the cellular and molecular mechanisms by which neurochemical systems modulate the activity of CNS networks underlying breathing and anxiety. The thesis is divided into two parts. The first part examines the mechanisms by which the neuromodulator/neurotransmitter...