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Skip to Search Results- 2Hegadoren, Kathleen M.
- 1Adu, Medard Kofi
- 1Al-Ghamdi,Mohammad S
- 1Al-Nuaimi, Saleem K
- 1Amritraj, Asha
- 1Amusan, Precious
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Impact of the COVID-19 Pandemic on Developmental Vulnerabilities and Mental Health: Implications for Children and Adolescents in Alberta Using an Evidence-Based Approach
DownloadFall 2024
This paper-based thesis presents a comprehensive investigation into developmental vulnerability and mental health-related utilization in young individuals, including physicians’ office visits, emergency department visits, and hospitalizations, utilizing population-level data. The primary...
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Fall 2023
This is a comprehensive examination of the diagnostic landscape in psychiatry and the role precision psychiatry might play in redefining how we classify illnesses. This thesis delves into three areas that currently exist in psychiatry today and is divided into five chapters. The first and second...
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Improving Child and Adolescent Mental Health Services: A Qualitative and Quantitative Exploration into the Current State of Services in Alberta, Canada
DownloadSpring 2023
Background There is a paucity of evidence-based research aimed at determining best-practice treatment in the context of child and adolescent mental health services (CAMHS). Despite the high prevalence of mental illness in youth, no gold-standard for treatment currently exists. Assessment tools...
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Perineuronal nets and their role in cognitive impairment in central nervous system diseases
DownloadFall 2023
Perineuronal nets (PNNs) are organized components of the extracellular matrix that surround mature neurons of the central nervous system (CNS). These structures have neuroprotective properties for host cells, provide structural and functional stability, and have been implicated in brain functions...
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Pharmacogenomics for Psychiatry: Focusing on Drug Metabolizing Enzymes and Transporters, with Validated Methodology for CYP2D6 and CYP2C19 Including for a Novel Sub-Haplotype
DownloadSpring 2022
Pharmacogenomics (PGx) is interested in the impact individual genetic makeup has on a patient’s response to pharmacological agents. In clinical practice, PGx has the potential of reducing adverse drug reactions (ADRs), which cost Canada $65 million dollars in the year 2018, as well as enhancing...
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Fall 2022
Background: Most discharged psychiatric patients in Alberta are offered follow-up appointments with Alberta Health Services (AHS) Addiction and Mental Health (A&MH) community providers. It is typical to wait weeks or months for a follow-up appointment, resulting in a substantial psychological...
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Repetitive Transcranial Magnetic Stimulation with and without Internet-delivered Cognitive Behaviour Therapy for the Treatment of Resistant Depression: Patient-centred Randomized Controlled Pilot Trial
DownloadFall 2022
Abstract Background: Major depression is a severe, disabling, and potentially lethal clinical disorder. Only about half of patients respond to an initial course of antidepressant pharmacotherapy. At least 15% of patients with major depression disorder (MDD) remain refractory to any treatment...
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Fall 2022
Suicide is a serious public health issue resulting in high mortality rates around the world. Trauma and adversity are strongly correlated with suicidal thoughts and behaviours. Memories associated with past trauma can contribute to significant distress in the present, creating a desire to escape...