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Skip to Search Results- 2Coulombe, Marilyne G.
- 2Kinnaird, Adam
- 2Srivastava, Nutan
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Aburahess, Salah
- 8Primary Biliary Cholangitis
- 7Inflammatory Bowel Disease
- 7Inflammatory bowel disease
- 6Endothelial cells
- 5Acute myeloid leukemia
- 5Mitochondria
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The Relationship (or Lack Thereof) Between Weight Loss and Health-Related Quality of Life in the Severely Obese
DownloadFall 2014
The impact of weight and weight loss on health-related quality of life (HRQL) in obese individuals and, in particular, the severely obese, is poorly understood. We completed a meta-analysis of published weight loss intervention trials; conducted cross-sectional analyses to examine...
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THE PSYCHOSOCIAL FUNCTIONING OF PATIENTS WITH INFLAMMATORY BOWEL DISEASE IN EARLY ADULTHOOD IS IMPAIRED
DownloadFall 2012
Inflammatory bowel disease is a chronic disease that is often diagnosed in childhood and adolescence. The objective of this study was to assess the impact of a diagnosis of IBD on the psychosocial functioning in early adulthood. This was a questionnaire-based cross-sectional study comparing...
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The prognosis and outcomes of patients with a ST-segment elevation myocardial infarction and the biochemical and clinical inflammatory response
DownloadSpring 2013
Acute myocardial infarction, and specifically coronary plaque rupture, has been associated with a systemic inflammatory cascade. Using multiple large clinical trial datasets, we sought to further understand the systemic and clinical inflammatory responses in patients with ST-elevation myocardial...
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The Prion Protein: Modulation of Potassium Channels and a Novel Mouse Model of a Disease-Causing Hydrophobic Domain Insertion Mutation
DownloadSpring 2016
Mercer, Robert Corrigan Curtis
Prion diseases are invariably fatal neurodegenerative diseases of humans and other mammals. While they can manifest as sporadic, infectious or genetic etiologies, the central event in prion disease is the structural conversion of the prion protein (PrPC) to an alternative conformer PrPSc. PrP is...
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The Prevalence and Risk Factors for Nontuberculous Mycobacterial Infection in Lung Transplant Patients and Its Impact on Patient Survival and Graft Function
DownloadFall 2020
Nontuberculous mycobacteria (NTM) are environmentally ubiquitous bacteria and frequent colonizers of immunocompetent and immunocompromised patients. NTM infections have been described in patients with chronic lung disease and post-lung transplantation. However, the risk factors for infection and...
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The perplexity of calcium-binding protein, spermatid-associated 1 (CABS1): A molecule that despite its name, is present beyond the reproductive tract, with ties to stress, and possessing an anti-inflammatory domain only preserved in simians
DownloadFall 2022
A protein in rat submandibular glands (SMG) led our group to research human calcium-binding protein, spermatid associated 1 (CABS1). In a model of lung inflammation in rats where neural input was interrupted, our group observed that SMG released an anti-inflammatory factor later identified as...
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Fall 2024
The neighbourhood food environment, defined as the exposure to (measured as availability, density, or distance to) healthy and unhealthy food outlets around places within which individuals gravitate, including home, schools, workplaces, and beyond, plays a complex role in influencing food intake...