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Skip to Search Results- 2Coulombe, Marilyne G.
- 2Kinnaird, Adam
- 2Srivastava, Nutan
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Aburahess, Salah
- 8Primary Biliary Cholangitis
- 7Inflammatory Bowel Disease
- 7Inflammatory bowel disease
- 6Endothelial cells
- 5Acute myeloid leukemia
- 5Mitochondria
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Spring 2018
Renal cell carcinoma comprises approximately 2-3% of all malignancies, with the majority, approximately 70%, being clear cell renal cell carcinoma (ccRCC). ccRCC features many cancer hallmarks such as suppressed mitochondrial glucose oxidation, apoptosis-resistance, angiogenesis, immune evasion,...
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Fall 2017
The two types of rejection identified in the Banff histopathologic diagnosis are T cell-mediated rejection (TCMR) and antibody-mediated rejection (ABMR). TCMR is most common early post-transplant while ABMR is the main cause of late graft loss. Kidney transplant TCMR is diagnosed histologically...
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Fall 2017
The adipocyte-derived lipokine, C16:1n7-palmitoleate, regulates a variety of functions such as systemic glucose and fatty acid metabolism. Under normal physiological conditions, palmitoleate levels are regulated by de novo lipogenesis. During pathological conditions where there are enhanced rates...
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Clinical and Angiographic Outcomes Associated with Surgical Revascularization of Angiographically Borderline 50-69% Coronary Artery Stenoses
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Objectives: Coronary artery bypass grafting improves outcomes in patients with multi-vessel coronary artery disease. Bypass of angiographically significant lesions ≥70% is recommended, yet little is known about the incidence/outcomes with bypasses of 50-69% angiographically borderline lesions...
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Spring 2017
Von Willebrand Factor (VWF) is a multimeric adhesive glycoprotein that is exclusively expressed in endothelial cells (EC) and megakaryocytes. This procoagulant protein is involved in maintaining primary hemostasis and thrombus formation. However, there are pathological and physiological...
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ENDOTHELIAL CELL HETEROGENEITY: A CORRELATION WITH THE VON WILLEBRAND FACTOR EXPRESSION IN DISTINCT ORGANS
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Endothelial cells (EC) of different organs exhibit heterogeneity in structure, function and gene expression pattern. This also extends to the pattern in which the highly endothelial-specific gene, von Willebrand Factor (VWF) is expressed. VWF is a multimeric adhesive, pro-coagulant glycoprotein...
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Community-Driven Research in the Canadian Arctic: Investigating the Effect of Dietary Exposure to Methylmercury on the Severity of Chronic Inflammation and Gastric Neoplasia in Populations with an Elevated Risk of Gastric Cancer
DownloadFall 2017
Introduction While gastric cancer has been declining in incidence for decades globally, it remains a major cause of death. Evidence suggests that Indigenous populations worldwide experience a higher burden of gastric cancer relative to non-Indigenous populations residing in the same geographic...