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Skip to Search Results- 2Coulombe, Marilyne G.
- 2Kinnaird, Adam
- 2Srivastava, Nutan
- 1Abdualla, Radya Y
- 1Abofayed, Hiatem Abdullah
- 1Aburahess, Salah
- 8Primary Biliary Cholangitis
- 7Inflammatory Bowel Disease
- 7Inflammatory bowel disease
- 6Endothelial cells
- 5Acute myeloid leukemia
- 5Mitochondria
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Fall 2014
Background: N-of-1 trials are prospectively planned, multiple crossover evaluations, conducted in individual patients. Evidence shows that a range of designs and statistical methods have been applied to N-of-1 trials. This thesis helps to provide a comprehensive understanding about the...
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Fall 2015
This thesis consists of 2 closely linked projects that evaluate the importance of depressive symptoms (hereafter, for brevity, referred to as “depression”) for short-term prognosis after general medical hospitalizations. Project 1 systematically reviews the literature to examine whether...
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Studying the Regulatory Effects of Betaretrovirus infection in the NOD.c3c4 mouse model of Primary Biliary Cholangitis
DownloadFall 2019
A human betaretrovirus (HBRV) has been previously characterized in patients with primary biliary cholangitis (PBC). HBRV shares between 91% to 99% nucleotide similarity with the mouse mammary tumor virus (MMTV). Retroviruses are known to suppress host immune responses by the presence of...
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Spring 2012
Stroke, a reduction in blood flow to the brain, activates various proteins that contribute to neuronal death. The matrix metalloproteinases (MMPs), specifically MMP2 and MMP9, are important in maintaining the blood brain barrier (BBB). After a stroke the BBB permeability increases which is...
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Fall 2019
Research is crucial for the development of treatment guidelines. Informed consent is an essential component to ensure the ethical integrity of research. An ideal informed consent should meet three requirements; disclosure of adequate information about the study, subjects understand the...
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Fall 2010
Mast cells are immune cells important in innate immunity. Besides their role in asthma and allergies, mast cells are critical effector cells against various pathogens. Mast cells are established to be protective against bacterial infections, but little is known about their functions in viral...
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Comparing contact investigations of tuberculosis cases among the Canadian Born Aboriginal and non-Aboriginal population in Alberta, Canada
DownloadSpring 2015
It is well established that the rates of tuberculosis (TB) among Aboriginal Peoples in Alberta are disproportionately higher than those in the Canadian-born 'other' population group (Jensen, Lau, Langlois-Klassen, et al., 2012). In addition, Aboriginal Peoples living on-reserve have higher rates...