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Skip to Search Results- 33Mass-spectrometry
- 24Chemistry
- 23Organic compounds. Synthesis.
- 22Metabolomics
- 21Capillary electrophoresis.
- 21Catalysis
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Development and Applications of Mass Spectrometric Methods for Proteome Analysis and Protein Sequence Characterization
DownloadFall 2013
Mass spectrometry (MS) is widely used in proteomic work for protein identification and characterization. A key to the success of MS for protein analysis is related to sample preparation. Current sample preparation methods do not meet all the needs of protein or proteome analysis. My thesis work...
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Spring 2021
Lipidomics aims to research lipid metabolism inside various samples or biological organisms. Through the research of lipidomics, information regarding the diversity, abundance, and function of lipids can determined. Although lipids can be categorized into 8 lipid classes, the variability between...
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Stereoselective Synthesis of β-Aminoalkylboronic Acid Derivatives Using 1,1-Diboron Compounds
DownloadSpring 2020
As an important class of chiral alkylboron compounds, α-aminoalkylboronic acids display distinct utility in medicinal chemistry as a bioisostere of α-amino acids and α-amino aldehydes, which is highlighted by the commercialization of two anticancer drugs (bortezomib and ixazomib) and one...
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A New Approach to Molecular Hydrodesulfurization Catalysts: Allyl-capped Trialkylphosphoranimide-bridged Late First-row Transition Metal Clusters
DownloadFall 2017
A series of new trialkylphosphoranimide allyl-capped clusters [M(ƞ3-allyl)(NPR)3]2, (M = Fe, Co or Ni, R = Et, tBu or Ph) were synthesized. The nickel dimers [Ni(ƞ3-allyl)(NPR3)]2, R = Et, Ph are diamagnetic and have been fully characterized using NMR spectroscopy, X-ray crystallography,...