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Characterizing Cerebral Degeneration in Amyotrophic Lateral Sclerosis with Texture Analysis
DownloadFall 2020
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is hallmarked by unrelenting and progressive wasting and paralysis of voluntary muscles. The classic pathology in ALS features neuronal loss, gliosis, and abnormal protein deposition in the upper and lower motor neurons (UMN...
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Spring 2019
The invention of magnetic resonance imaging (MRI) has advanced the diagnosis of diseases dramatically as it is capable of producing high-quality images of soft tissues non-invasively and safely. However, the high volume of MRI images also means heavy workloads for physicians, which results in...
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ON THE ABILITY OF PROTECTIVE HEADGEAR TO ALTER SKULL AND BRAIN KINETICS DURING BLAST AND IMPACT: AN EXPERIMENTAL STUDY USING A SURROGATE MODEL OF THE HUMAN HEAD WITH NOVEL INSTRUMENTATION
DownloadSpring 2019
Blast-induced traumatic brain injury (bTBI) has become increasingly prevalent among military personnel over recent years. Head protection is fielded to mitigate the amount of energy imparted to head, as a result of ballistic and impact exposure. Despite the efficacy of contemporary headgear in...
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Oscillating Gradient Spin Echo (OGSE): A Study of Short Diffusion Time Effects in Human Brain at 3T
DownloadSpring 2020
Diffusion-weighted magnetic resonance imaging (DWI) is a non-invasive MRI technique that is sensitive to the diffusion of water molecules within the body. Its ability to encode water displacements enables it to detect changes in neural microstructure, such as those due to normal healthy aging or...