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- 3Fliegel, Larry
- 2Harrington, Michael J.
- 2Hegele, Robert A.
- 2Wang, J.
- 2Young, T. Kue
- 26Graduate and Postdoctoral Studies (GPS), Faculty of
- 26Graduate and Postdoctoral Studies (GPS), Faculty of /Theses and Dissertations
- 11Biological Sciences, Department of
- 8Biological Sciences, Department of/Journal Articles (Biological Sciences)
- 4Agricultural, Food and Nutritional Science, Department of
- 4Agricultural, Food and Nutritional Science, Department of/Journal Articles (Agricultural, Food and Nutritional Science)
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Manipulation of Seed Carbon Flow from Cellulose to Lipid and Protein Biosynthesis in Arabidopsis to Accelerate the Characterization of Protein-Related Genes in Canola
DownloadFall 2023
Canola (Brassica napus L.) is the major oilseed crop in Canada. After oil extraction, the protein-rich seed meal (around 40% protein) serves as a nutritious feedstock for animals and the protein fraction has potential for human consumption. However, excess fiber in the seed meal (about 33%) can...
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Fall 2021
Headgear are cranial appendages usually seen in males of infraorder Pecora. This trait is used to determine hierarchy and gain access to mates. In bighorn sheep, males or rams have impressively large horns that are made of keratin and cancellous bone. These horns are used in yearly combats to...
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Innate Immunity and the Retinal Pigment Epithelium in Gene Therapy for Inherited Retinal Disorders
DownloadFall 2021
Background: The photoreceptors are post-mitotic (no longer dividing), so the eye has evolved several unique immunological mechanisms to protect the photoreceptors and prevent vision loss. Inherited retinal disorders occur when mutations disrupt normal retinal function and photoreceptors die....
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Fall 2021
Disease resilience is defined as an animal’s ability to maintain a high level of performance in the face of disease challenges caused by multiple pathogens, as is often the case in commercial pig farms. Therefore, disease resilience is anticipated to be critical to the profitability of the pig...
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Fall 2021
Clubroot disease, caused by Plasmodiophora brassicae, is a major threat to canola production. Cultivation of resistant cultivars is the key component in managing this disease. Canola is an important oilseed crop in the world; this includes the allopolyploid species Brassica napus L. (AACC genome,...
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Spring 2020
Collisions of motorized transport with wildlife impact a wide range of species and can cause injuries and economic losses to people. On roads, vehicle collisions with animals have been studied extensively, resulting in mitigation measures that reduce collisions by segregating animals and...
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Anti-Cancer Mechanism of Trastuzumab via Blocking Nuclear HER2 Function and Epigenetic Mechanism of Resistance
DownloadSpring 2020
HER2 receptor tyrosine kinase (encoded by ERBB2 gene) is overexpressed in approximately 25% of all breast cancer tumors (known as HER2-positive breast cancers). Overexpression of HER2 causes overactivation of downstream receptor tyrosine kinase pathways including PI3K/Akt and MAPK pathways and is...
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Fall 2020
Rac1 is a small GTPase that belongs to the Rho family. Like other Rho family GTPases, it mediates a plethora of cellular effects, including regulation of cytoarchitecture, cell size, cell adhesion, cell polarity, cell motility, proliferation, apoptosis/survival, and membrane trafficking. The...
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Fall 2019
The development of efficacious anticancer therapies has significantly improved the prognosis of childhood cancer patients at the price of predisposing survivors to extensive chronic health problems. Although not fatal, reducing treatment-related hearing loss (ototoxicity) among childhood cancer...
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2019-01-01
Nair, Sindhu G., Loppnow, Glen R.
It has been well established that mutations in K-Ras and N-Ras proto-oncogenes can convert them into active oncogenes. Current molecular cancer research has been focused on determining the key steps by which cellular genes become oncogenes and not on the underlying and fundamental chemical damage...