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Spring 2014

El-Thaher, Nayef

Conversion of protein-rich biomass waste into value-added industrial products via chemical cross-linking reactions was explored. Two types of cross-linking reagents were investigated: dialdehydes and epoxy resins. Reaction chemistry was the main focus of this investigation and the main reaction...

Fall 2009

Molavi, Ommoleila

Signal Transducer and Activator of Transcription 3 (STAT3), a common oncogenic mediator, is constitutively activated in many types of human cancers and plays a critical role in tumor growth and cancer immune evasion. The focus of this dissertation is the delivery of STAT3 inhibitor cucurbitacins...

Fall 2015

Murphy, Jeffrey Nathaniel

2015 marks the 50th anniversary of Moore's law, which has described the exponential progress in semiconductor patterning technologies, enabling creation of smaller circuitry features at greater densities. These continued hardware developments, economically mass manufactured, have made possible...

Spring 2017

Amin, Muhammad Ruhul

Nanomechanical resonators are explored as mass sensors and molecular sensors due to their high sensitivity and real time label-free detection ability, respectively. One downside of mechanical molecular sensing is the lack of chemical information carried in the signal. For this reason, a...

Fall 2015

Perron, David H.

Nanoplasmonic devices have received much attention in recent years due to their ability to confine light below the diffraction limit, thereby providing a potential route to the creation of nanometer-scale integrated photonic devices. However, with the strong confinement of light come large...

Spring 2015

Biabangard Oskouyi, Amirhossein

In this thesis, a novel three-dimensional continuum percolation model based on Monte Carlo simulation approach was developed and employed to investigate the percolation behavior of the electrically insulating matrix reinforced with conductive nanoplatelet fillers such as graphene. The...

Fall 2019

Thapa, Bindu

Targeting a single pathway is not enough to treat cancer because of compensatory mechanisms against anticancer therapy via alternative molecular pathways for survival and proliferation of malignant cells. Given the unacceptable toxicity associated with conventional therapy, nucleic acids such as...

Spring 2021

Hartley, Kendra Jade

Hand injuries, due to impact, are common workplace injuries. Many work gloves afford impact protection through design of add-on components known as bumpers. Glove design criteria are complex (e.g., limitations from human factors, dexterity, use case, hand size variability) and commercial bumpers...

Fall 2010

Abbasi Dezfouli, Meysam

Gene delivery for therapeutic purposes is quickly emerging as the best potential treatment option for inherited genetic diseases and cancer. Viral gene carriers have been the choice for this purpose due to their high efficiency, but harmful immunogenic and oncogenic host reactions have limited...

Spring 2019

Jami, Rafat

Long chained polymers were evaluated for their impact on reducing pipe erosion during two-phase flow. The research study was compartmentalized into three categories. One of the components of this study investigated the erosion of different materials in an attempt to find a faster eroding...