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Skip to Search Results- 1Abazari Torqabeh, Alireza
- 1Abbasi Dezfouli, Meysam
- 1Ahmed, Sabbir
- 1Akin, Oguz
- 1Akpuh, Jude
- 1Amin, Muhammad Ruhul
- 11Department of Chemical and Materials Engineering
- 9Department of Mechanical Engineering
- 5Department of Chemistry
- 3Department of Biological Sciences
- 3Department of Electrical and Computer Engineering
- 2Department of Biomedical Engineering
- 2Choi, Phillip (Chemical and Materials Engineering)
- 2Goss, Greg (Biological Sciences)
- 2Liu, Yang (Civil and Environmental Engineering)
- 1Antoniuk, Tim (Industrial Design)
- 1Backhouse, Chris (Electrical and Computer Engineering, University of Waterloo)
- 1Boluk, Yaman (Civil and Environmental Engineering)
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Lipid Modified Polymers for Transfection of Human CRL Fibroblasts, and for siRNA Mediated MDR Reversal in Melanoma Cancer Therapy
DownloadFall 2010
Gene delivery for therapeutic purposes is quickly emerging as the best potential treatment option for inherited genetic diseases and cancer. Viral gene carriers have been the choice for this purpose due to their high efficiency, but harmful immunogenic and oncogenic host reactions have limited...
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Fall 2015
Caverhill-Godkewitsch, Saul A.
The infrastructure necessary to support diagnostic and pathogen-detection processes does not exist in some regions of the world that need it most. Access to fast, inexpensive and portable diagnostic infrastructure could be a solution to this problem. Next generation lab-on-chip (LOC) systems that...
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Modeling the transport of cryoprotective agents in articular cartilage for cryopreservation
DownloadSpring 2011
Loading vitrifiable concentrations of cryoprotective agents is an important step for cryopreservation of biological tissues by vitrification for research and transplantation purposes. This may be done by immersing the tissue in a cryoprotective agent (CPA) solution, and increasing the...
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Fall 2009
The Dual Failure Restorability (DFR) problems involve the design of network topology to be restorable in the event of single and dual failures scenarios. We developed new integer linear programming (ILP) models to optimally design mesh topology networks with various survivability schemes; span...
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Nano-scale studies of the assembly, structure and properties of hybrid organic-silicon systems
DownloadFall 2011
Advancements in the field of electronics might be achieved by future molecular scale devices. Hybrid organic-silicon structures have the potential to overcome many challenges facing the use of molecules as devices while maintaining the ability to interface with traditional silicon technology. The...
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Spring 2017
Oilsands tailings are a waste product comprising primarily a stable alkaline suspension of clay in water. This waste product of oilsands mining is environmentally hazardous to store and expensive to safely dispose of. This work presents two novel ideas for dealing with the waste. The first is...
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Spring 2012
The following thesis describes original studies assessing the gene delivery efficacy of novel non-viral carrier combinations. The first panel of non-viral carriers tested are termed AVPs (artificial viral particles), in reference to their structural similarity to enveloped viruses, and were...
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Fall 2010
This study experimentally evaluated wheat straw slurry pipelines. Tests were conducted to determine the particle properties of the biomass mixed in water over time. The saturated particle density of 1,060kg/m3 was reached after 24 hours, while the saturated moisture contents of 78.5% and 79.5%...
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Fall 2019
Targeting a single pathway is not enough to treat cancer because of compensatory mechanisms against anticancer therapy via alternative molecular pathways for survival and proliferation of malignant cells. Given the unacceptable toxicity associated with conventional therapy, nucleic acids such as...