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Diagnosing Clinically Significant Dehydration in Children with Acute Gastroenteritis Using Noninvasive Methods: A Meta-Analysis
Download2015
Milne, Andrea, Hartling, Lisa, Vandermeer, Ben, Freedman, Stephen B.
OBJECTIVE: To determine the most accurate, noninvasive method of assessing dehydration. STUDY DESIGN: The following data sources were searched: electronic databases, gray literature, scientific meetings, reference lists, and authors of unpublished studies. Eligible studies were comparative...
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Do health care institutions value research? A mixed methods study of barriers and facilitators to methodological rigor in pediatric randomized trials.
Download2012
Scott, S. D., Hamm, M. P., Hartling, L., Klassen, T. P., Moher, D.
Background Pediatric randomized controlled trials (RCTs) are susceptible to a high risk of bias. We examined the barriers and facilitators that pediatric trialists face in the design and conduct of unbiased trials. Methods We used a mixed methods design, with semi-structured interviews building...
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Do sugar-sweetened beverages cause adverse health outcomes in children? A systematic review protocol
Download2014
Ziegler, Paula, Hamel, Candyce, Gow, Robert, Hutton, Brian, Pound, Catherine, Hadjiyannakis, Stasia, Sharma, Arya, Myers, Esther, Willows, Noreen, Singh, Kavita, Fenton, Shannon, Salewski, Erinn, Shrier, Ian, Ansari, Mohammed T., Stevens, Adrienne, O'Hara, Kathryn, Moher, David, Bjerre, Lise M., Tremblay, Mark
Background Cardiovascular disease and type 2 diabetes are examples of chronic diseases that impose significant morbidity and mortality in the general population worldwide. Most chronic diseases are associated with underlying preventable risk factors, such as elevated blood pressure, high blood...
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Fall 2014
Infant face and throat replicas are used in research laboratories to compare the effectiveness of different valved holding chamber and face mask designs. The use of soft face models is thought to provide a better representation of mask dead volume and face mask seal than hard face models....
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Fall 2020
Introduction By 2030, 1/100 Canadians are predicted to be diagnosed with inflammatory bowel diseases (IBD); approximately 25% of cases are diagnosed in children. IBD include Crohn disease (CD) and ulcerative colitis (UC), and manifest with chronic gastrointestinal inflammation. Pathogenesis...
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Efficacy and side-effect profiles of lactulose, docusate sodium, and sennosides compared to PEG in opioid-induced constipation: A systematic review
DownloadSpring 2012
Opioid-induced constipation (OIC) is an unpleasant and ubiquitous side effect of opioid treatment. Ineffective treatment of OIC can result in decreased adherence to opioid therapy, decreased quality of life, and increased morbidity and mortality. The constipating effects of opioids result from...
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Enrollment in Multidisciplinary Clinical Care for Pediatric Weight Management: Predictors, Reasons, Facilitators, and Recommendations
DownloadFall 2017
Background: One-third of Canadian children meet the criteria for overweight or obesity. While multidisciplinary clinical care (MCC) can be effective to manage pediatric obesity, many eligible children are not referred to this level of care and many of those who are referred do not enroll in...
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2013-02-15
Klassen, Terry P., Plint, Amy C., Vandermeer, Ben, Tjosvold, Lisa, Hartling, Lisa, Fernandes, Ricardo M., Patel, Hema, Bialy, Liza M., Johnson, David W.
Background: Bronchodilators are commonly used for acute bronchiolitis, despite uncertain effectiveness. Objectives: To examine the efficacy and safety of epinephrine in children less than two with acute viral bronchiolitis. Search methods: We searched CENTRAL (2010, Issue 3) which contains the...
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2014
Wilson, D. M., Thomas, R. E., Birch, S., Woytowich, B.
Case management was initiated in the 1970s to reduce care discontinuity. A literature review focused on end-of-life (EOL) case management identified 17 research articles, with content analysis revealing two themes: (a) seeking to determine or establish the value of EOL case management and (b)...
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Exploring anthropometric and laboratory differences in children of varying ethnicities with Celiac disease
Download2014-01-01
Rajani, Seema, Alzaben, Abeer, Shirton, Leanne, Persad, Rabindranath, Hyuhn, Hien Q., Mager, Diana R., Turner, Justine M.
BACKGROUND: Celiac disease (CD) is a common autoimmune disorder with an increasing prevalence, including in ethnic minorities. OBJECTIVE: To report the frequency of CD diagnosis in ethnic minorities presenting to a Canadian pediatric celiac clinic and to determine whether ethnic differences exist...